The study on the antioxidant activity of polysaccharides isolated from Polygonatum odoratum (Mill.) Druce

Q4 Chemistry Mongolian Journal of Chemistry Pub Date : 2020-12-31 DOI:10.5564/mjc.v21i47.1154
Wulan Gerile, Naranchimeg Dorjpalam, W. Gui, Liang Xu, Jinglin Liu
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引用次数: 1

Abstract

The polysaccharides isolated from Polygonatum odoratum (Mill.) Druce (POPs) by water extraction, after precipitation with ethanol were purified through deproteinization, decolorization, dialysis, and column chromatography leading to a purified polysaccharide (POPs-I) content of 90.7 %. The scavenging of oxygen free radicals and inhibition of lipid peroxidation (LPO) by POPs-I were analyzed using a colorimetric method. The results showed that the hydroxyl radical scavenging ability of the polysaccharides was weaker than that of benzoic acid, but stronger than those of ascorbic acid and mannitol, and that the superoxide anion radical scavenging ability was inferior to those of all three. When the concentration was higher than 1.0 mg/mL, the POPs-I could inhibit LPO by superoxide anion radicals to a certain degree. Therefore, this work suggests that POPs-I are potential antioxidant agents in medicine and functional food.
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玉黄精多糖抗氧化活性的研究Druce
从玉竹药材中分离得到的多糖经水提、乙醇沉淀后,经脱蛋白、脱色、透析、柱色谱等方法纯化,纯化后的多糖(POPs-I)含量为90.7%。用比色法分析了POPs-I对氧自由基的清除作用和对脂质过氧化(LPO)的抑制作用。结果表明,多糖对羟基自由基的清除能力弱于苯甲酸,但强于抗坏血酸和甘露醇,对超氧阴离子自由基的清理能力不如三者。当浓度高于1.0mg/mL时,POPs-I对超氧阴离子自由基LPO有一定的抑制作用。因此,这项工作表明POPs-I在医学和功能性食品中是潜在的抗氧化剂。
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来源期刊
Mongolian Journal of Chemistry
Mongolian Journal of Chemistry Materials Science-Materials Chemistry
CiteScore
1.10
自引率
0.00%
发文量
5
审稿时长
20 weeks
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