Anujin Lkhagvadorj, Tserendolgor Batsukh, A. Tsend-Ayush
Development of bio-compatible, bio-safe and environmentally friendly nanoparticles is a matter of urgency for research in the field of nanotechnology. In this study, we aimed to prepare zinc oxide nanoparticles from Mongolian honey as raw material and to determine its biological activities. Honey-based zinc oxide nanoparticles were obtained by green synthesis method, and their characteristics and biological activities were evaluated. Developed zinc oxide nanoparticles from Khentii honey and Selenge honey were at a size of 16.02 nm and 95.23 nm, respectively. A characteristic band of Khentii honey-based zinc oxide nanoparticles was observed at 466 cm–1 and a band of Selenge honey-based zinc oxide nanoparticles was also observed at 434 cm–1. Antibacterial and photocatalytic effects were detected for the developed nanoparticles. The study suggested that newly synthesized honey-based zinc oxide nanoparticles might be an effective tool against bacterial infection.
{"title":"Antibacterial and photocatalytic effects of newly synthesized zinc oxide nanoparticles derived from Mongolian honey","authors":"Anujin Lkhagvadorj, Tserendolgor Batsukh, A. Tsend-Ayush","doi":"10.5564/mjc.v25i51.3119","DOIUrl":"https://doi.org/10.5564/mjc.v25i51.3119","url":null,"abstract":"Development of bio-compatible, bio-safe and environmentally friendly nanoparticles is a matter of urgency for research in the field of nanotechnology. In this study, we aimed to prepare zinc oxide nanoparticles from Mongolian honey as raw material and to determine its biological activities. Honey-based zinc oxide nanoparticles were obtained by green synthesis method, and their characteristics and biological activities were evaluated. Developed zinc oxide nanoparticles from Khentii honey and Selenge honey were at a size of 16.02 nm and 95.23 nm, respectively. A characteristic band of Khentii honey-based zinc oxide nanoparticles was observed at 466 cm–1 and a band of Selenge honey-based zinc oxide nanoparticles was also observed at 434 cm–1. Antibacterial and photocatalytic effects were detected for the developed nanoparticles. The study suggested that newly synthesized honey-based zinc oxide nanoparticles might be an effective tool against bacterial infection.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"77 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141123576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The focus of this study is on the synthesis of organic fluorescent and thermally stable polyamides using an s-triazine frame. Coumarin and n-phenyl anthranilic acid have been utilized as bulky pendent groups in the synthesis of the monomer, resulting in polyamides with two groups that enhance stability and fluorescence. The synthesized polyamides have been characterized using a variety of techniques. The thermal stability of the polyamides has been studied using thermogravimetric analysis. These polyamides offer appealing features such as fluorescence and enhanced thermal stability, making them significant for a wide range of applications, including biosensors, clean energy technologies, and explosive sensing.
{"title":"Engineering polyamide materials: s-triazine framework with specialized bulky side chains for advanced applications","authors":"Deep Bhalani, Sabir Khan Pathan, Jignasa V.Modh","doi":"10.5564/mjc.v25i51.3104","DOIUrl":"https://doi.org/10.5564/mjc.v25i51.3104","url":null,"abstract":"The focus of this study is on the synthesis of organic fluorescent and thermally stable polyamides using an s-triazine frame. Coumarin and n-phenyl anthranilic acid have been utilized as bulky pendent groups in the synthesis of the monomer, resulting in polyamides with two groups that enhance stability and fluorescence. The synthesized polyamides have been characterized using a variety of techniques. The thermal stability of the polyamides has been studied using thermogravimetric analysis. These polyamides offer appealing features such as fluorescence and enhanced thermal stability, making them significant for a wide range of applications, including biosensors, clean energy technologies, and explosive sensing.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"84 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140984538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A total of 114 Mongolian plant species were subjected to cytotoxicity screening against liver (HepG2), colon (HCT116), breast (MCF7), and cervical (HeLa) cancer cell lines. Among them, ethanolic extracts of Androsace incana, Artemisia rutifolia, Saussurea amara, and Inula salsoloides exhibited remarkable cytotoxicity, with IC50 values below 1.5 μg/mL against at least 2 tested cell lines when treated for 48 hours. Erysimum flavum, Juniperus sibirica, and Stellaria dichotoma demonstrated selective cytotoxicity against specific cancer cell lines. Extracts from 23 plant species, such as Artemisia xerophytica, Ajania trifida, Melandrium brachypetalum, Brachanthemum mongolicum, and Rhinanthus songaricus, showed moderate toxicity. Further research on the phytochemicals and biological activities of these species is crucial for a deeper understanding and potential applications. These screening results of the cytotoxic effects of numerous Mongolian plants could establish a foundational dataset for subsequent comprehensive studies on the screened plants.
{"title":"Cytotoxicity screening of 114 Mongolian plant extracts on liver, colon, breast, and cervix cancer cell lines","authors":"Sarangerel Oidovsambuu, Tuul Tsagaantsooj, Davaapurev Bekh-Ochir, Nomin Myagmar, Indra Batjikh, Saruul Erdenebileg, Orgilkhatan Munkhuu, O. Oidovsambuu, Batkhuu Javzan","doi":"10.5564/mjc.v25i51.2934","DOIUrl":"https://doi.org/10.5564/mjc.v25i51.2934","url":null,"abstract":"A total of 114 Mongolian plant species were subjected to cytotoxicity screening against liver (HepG2), colon (HCT116), breast (MCF7), and cervical (HeLa) cancer cell lines. Among them, ethanolic extracts of Androsace incana, Artemisia rutifolia, Saussurea amara, and Inula salsoloides exhibited remarkable cytotoxicity, with IC50 values below 1.5 μg/mL against at least 2 tested cell lines when treated for 48 hours. Erysimum flavum, Juniperus sibirica, and Stellaria dichotoma demonstrated selective cytotoxicity against specific cancer cell lines. Extracts from 23 plant species, such as Artemisia xerophytica, Ajania trifida, Melandrium brachypetalum, Brachanthemum mongolicum, and Rhinanthus songaricus, showed moderate toxicity. Further research on the phytochemicals and biological activities of these species is crucial for a deeper understanding and potential applications. These screening results of the cytotoxic effects of numerous Mongolian plants could establish a foundational dataset for subsequent comprehensive studies on the screened plants.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly contagious and has caused widespread loss of life. In the quest to find effective antiviral agents, attention has turned to oxadiazole derivatives, which are known for their potential antiviral properties in such as CoViTris2020, ChloViD2020, etc. To evaluate their effectiveness, molecular docking and molecular dynamics simulations are conducted for various oxadiazole derivative in interactions with critical proteins involved in the viral infection process. These proteins encompass transmembrane-serine-2 (TMPRSS2), 3-chymotrypsin-like-protease (3CLpro), angiotensin-converting-enzyme-2 (ACE2), and papain-like-protease (PLpro). The study shows that the oxadiazole derivatives exhibited their most stable complexes when interacting with TMPRSS2 in comparison to 3CLpro, ACE2, and PLpro. In particular, Oxa8 displayed a binding energy of -6.52 kcal/mol with TMPRSS2. In contrast, the binding energies with ACE2, 3CLpro, and PLpro were -5.74, -4.56, and -5.56 kcal/mol, respectively. RMSD analysis during MD simulations demonstrated that the complex structure remained consistently stable. During the initial 2 ns, the RMSD value for the ligand concerning its interaction with the protein backbone hovered around 2 Å, indicating a sustained level of structural stability. In conclusion, this study suggests that oxadiazole derivative Oxa8 holds promise as a potential inhibitor of SARS-CoV-2, particularly due to its strong binding affinity with TMPRSS2 and its enduring structural stability observed in molecular dynamics simulations.
{"title":"Study of Oxadiazole derivatives as precursor for multi-functional inhibitor to SARS-CoV-2: A detailed virtual screening analysis","authors":"Vikash Kumar, Sumit Kumar","doi":"10.5564/mjc.v25i51.2909","DOIUrl":"https://doi.org/10.5564/mjc.v25i51.2909","url":null,"abstract":"SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly contagious and has caused widespread loss of life. In the quest to find effective antiviral agents, attention has turned to oxadiazole derivatives, which are known for their potential antiviral properties in such as CoViTris2020, ChloViD2020, etc. To evaluate their effectiveness, molecular docking and molecular dynamics simulations are conducted for various oxadiazole derivative in interactions with critical proteins involved in the viral infection process. These proteins encompass transmembrane-serine-2 (TMPRSS2), 3-chymotrypsin-like-protease (3CLpro), angiotensin-converting-enzyme-2 (ACE2), and papain-like-protease (PLpro). The study shows that the oxadiazole derivatives exhibited their most stable complexes when interacting with TMPRSS2 in comparison to 3CLpro, ACE2, and PLpro. In particular, Oxa8 displayed a binding energy of -6.52 kcal/mol with TMPRSS2. In contrast, the binding energies with ACE2, 3CLpro, and PLpro were -5.74, -4.56, and -5.56 kcal/mol, respectively. RMSD analysis during MD simulations demonstrated that the complex structure remained consistently stable. During the initial 2 ns, the RMSD value for the ligand concerning its interaction with the protein backbone hovered around 2 Å, indicating a sustained level of structural stability. In conclusion, this study suggests that oxadiazole derivative Oxa8 holds promise as a potential inhibitor of SARS-CoV-2, particularly due to its strong binding affinity with TMPRSS2 and its enduring structural stability observed in molecular dynamics simulations.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139817262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly contagious and has caused widespread loss of life. In the quest to find effective antiviral agents, attention has turned to oxadiazole derivatives, which are known for their potential antiviral properties in such as CoViTris2020, ChloViD2020, etc. To evaluate their effectiveness, molecular docking and molecular dynamics simulations are conducted for various oxadiazole derivative in interactions with critical proteins involved in the viral infection process. These proteins encompass transmembrane-serine-2 (TMPRSS2), 3-chymotrypsin-like-protease (3CLpro), angiotensin-converting-enzyme-2 (ACE2), and papain-like-protease (PLpro). The study shows that the oxadiazole derivatives exhibited their most stable complexes when interacting with TMPRSS2 in comparison to 3CLpro, ACE2, and PLpro. In particular, Oxa8 displayed a binding energy of -6.52 kcal/mol with TMPRSS2. In contrast, the binding energies with ACE2, 3CLpro, and PLpro were -5.74, -4.56, and -5.56 kcal/mol, respectively. RMSD analysis during MD simulations demonstrated that the complex structure remained consistently stable. During the initial 2 ns, the RMSD value for the ligand concerning its interaction with the protein backbone hovered around 2 Å, indicating a sustained level of structural stability. In conclusion, this study suggests that oxadiazole derivative Oxa8 holds promise as a potential inhibitor of SARS-CoV-2, particularly due to its strong binding affinity with TMPRSS2 and its enduring structural stability observed in molecular dynamics simulations.
{"title":"Study of Oxadiazole derivatives as precursor for multi-functional inhibitor to SARS-CoV-2: A detailed virtual screening analysis","authors":"Vikash Kumar, Sumit Kumar","doi":"10.5564/mjc.v25i51.2909","DOIUrl":"https://doi.org/10.5564/mjc.v25i51.2909","url":null,"abstract":"SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly contagious and has caused widespread loss of life. In the quest to find effective antiviral agents, attention has turned to oxadiazole derivatives, which are known for their potential antiviral properties in such as CoViTris2020, ChloViD2020, etc. To evaluate their effectiveness, molecular docking and molecular dynamics simulations are conducted for various oxadiazole derivative in interactions with critical proteins involved in the viral infection process. These proteins encompass transmembrane-serine-2 (TMPRSS2), 3-chymotrypsin-like-protease (3CLpro), angiotensin-converting-enzyme-2 (ACE2), and papain-like-protease (PLpro). The study shows that the oxadiazole derivatives exhibited their most stable complexes when interacting with TMPRSS2 in comparison to 3CLpro, ACE2, and PLpro. In particular, Oxa8 displayed a binding energy of -6.52 kcal/mol with TMPRSS2. In contrast, the binding energies with ACE2, 3CLpro, and PLpro were -5.74, -4.56, and -5.56 kcal/mol, respectively. RMSD analysis during MD simulations demonstrated that the complex structure remained consistently stable. During the initial 2 ns, the RMSD value for the ligand concerning its interaction with the protein backbone hovered around 2 Å, indicating a sustained level of structural stability. In conclusion, this study suggests that oxadiazole derivative Oxa8 holds promise as a potential inhibitor of SARS-CoV-2, particularly due to its strong binding affinity with TMPRSS2 and its enduring structural stability observed in molecular dynamics simulations.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"289 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139877282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neolamarckia cadamba Roxb., a plant commonly used in Indian traditional medicines, has been recognized for its anthelmintic properties. This study aimed to evaluate the in vitro anthelmintic activity of N. cadamba fruit extracts againstAscaridia galli (roundworm), Raillietina spiralis (tapeworm), and Pheretima posthuma (Indian adult earthworm). The hydro-methanolic extract of N. cadamba fruits exhibited superior anthelmintic activity compared to the ethyl acetate extract. Phytochemical analysis of the extracts revealed the presence of phenols, tannins, saponins, glycosides, phytosterols, flavonoids, and terpenoids. Furthermore, the contents of phenolics, flavonoids, proanthocyanidins, and anthocyanins in the fruit extracts were quantified. The quantitative analysis of total phenolic content of extracts revealved that hydromethanolic extract contains higher quantity of phenolics, flavonoids, proanthocyanidins, and anthocyanins in comparision to the ethylacetate extract. These findings support the observation that hydro-methanolic extract of N. cadamba fruits exhibited superior anthelmintic activity compared to the ethyl acetate extract because polyphenolic compounds are well established for their anthelmintic activity.
{"title":"Phytochemical investigation and in vitro anthelmintic evaluation of extracts of Wild Cinchona (Neolamarckia cadamba Roxb.) fruits","authors":"Praveen Kumar, L. Tripathi, Amita Verma","doi":"10.5564/mjc.v24i50.2269","DOIUrl":"https://doi.org/10.5564/mjc.v24i50.2269","url":null,"abstract":"Neolamarckia cadamba Roxb., a plant commonly used in Indian traditional medicines, has been recognized for its anthelmintic properties. This study aimed to evaluate the in vitro anthelmintic activity of N. cadamba fruit extracts againstAscaridia galli (roundworm), Raillietina spiralis (tapeworm), and Pheretima posthuma (Indian adult earthworm). The hydro-methanolic extract of N. cadamba fruits exhibited superior anthelmintic activity compared to the ethyl acetate extract. Phytochemical analysis of the extracts revealed the presence of phenols, tannins, saponins, glycosides, phytosterols, flavonoids, and terpenoids. Furthermore, the contents of phenolics, flavonoids, proanthocyanidins, and anthocyanins in the fruit extracts were quantified. The quantitative analysis of total phenolic content of extracts revealved that hydromethanolic extract contains higher quantity of phenolics, flavonoids, proanthocyanidins, and anthocyanins in comparision to the ethylacetate extract. These findings support the observation that hydro-methanolic extract of N. cadamba fruits exhibited superior anthelmintic activity compared to the ethyl acetate extract because polyphenolic compounds are well established for their anthelmintic activity.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"57 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139155748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ha Nguyen Manh, None Long Ha Phuong, None Dat Tran Phuc, None Huong Tran Thi
A Fenton-like catalyst MnO2-Fe3O4/SiO2 is synthesized via a two-step approach. The prepared composite has a mesoporous structure and a high surface area of 190 m2/g. The XRD pattern describes a specific peak of Fe3O4 magnetite on the baseline of amorphous silica. Furthermore, the FTIR spectra not only show the height assigned to stretching vibrations of Si-O-Si bonds, and Fe–O–Fe connections but also exhibit a small peak that matches the Mn–O bonds. SEM images exhibit a porous network structure of the composites with some holes among 30 – 100 nm clusters. The activity of the catalyst is determined in a paracetamol degradation as a Fenton oxidation. The paracetamol removal efficiency is at 85.6% with the optimal condition as initial pH 3, catalyst dosage of 0.15 g/50mL and H2O2 concentration of 1 mL/50 mL. In addition, the catalyst can be reused at least 5 times with a low reduction of the catalytic activity from 85.6% to 80.8%. The experiment results open a direction that has high efficiency in the treatment process of excess paracetamol in pharmacy wastewater.
{"title":"Application of the Fenton-like agent based on magnetic iron and manganese oxide in the degradation process of paracetamol in water","authors":"Ha Nguyen Manh, None Long Ha Phuong, None Dat Tran Phuc, None Huong Tran Thi","doi":"10.5564/mjc.v24i50.2890","DOIUrl":"https://doi.org/10.5564/mjc.v24i50.2890","url":null,"abstract":"A Fenton-like catalyst MnO2-Fe3O4/SiO2 is synthesized via a two-step approach. The prepared composite has a mesoporous structure and a high surface area of 190 m2/g. The XRD pattern describes a specific peak of Fe3O4 magnetite on the baseline of amorphous silica. Furthermore, the FTIR spectra not only show the height assigned to stretching vibrations of Si-O-Si bonds, and Fe–O–Fe connections but also exhibit a small peak that matches the Mn–O bonds. SEM images exhibit a porous network structure of the composites with some holes among 30 – 100 nm clusters. The activity of the catalyst is determined in a paracetamol degradation as a Fenton oxidation. The paracetamol removal efficiency is at 85.6% with the optimal condition as initial pH 3, catalyst dosage of 0.15 g/50mL and H2O2 concentration of 1 mL/50 mL. In addition, the catalyst can be reused at least 5 times with a low reduction of the catalytic activity from 85.6% to 80.8%. The experiment results open a direction that has high efficiency in the treatment process of excess paracetamol in pharmacy wastewater.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"AES-19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135112711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosemary leaf essential oil (RoEO) is extracted using steam distillation. The aim of study is to determine physicochemical characteristics of essential oil (EO), such as acid/saponification/esterification index, relative/absolute density, freezing point, and fragrance retention. The chemical composition of EOs was analyzed by gas chromatography-mass spectrometry (GC-MS) method and identified 50 volatile compounds, of which α-Pinene (33.76%), 1,8-Cineole (18.47%), and Levoverbenone (6.11%) constituted the highest proportions in EO. The antioxidant capacity (AC) of the EO was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method with a half-maximum inhibitory concentration (IC50) of 425.473 mg/mL. In particular, antibacterial activity (AA) by the paper plate diffusion method for susceptibility testing to essential oil showed that RoEO strongly inhibited the growth of four tested bacterial strains (Staphylococcus aureus, Bacillus cereus, Salmonella typhimurium, and Escherichia coli). Perhaps, it is possible to apply RoEO in the food industry and other fields owing to the good properties of RoEO.
{"title":"Chemical profile and biological properties of the essential oil of Rosemary leaves (Rosmarinus officinalis L.)","authors":"Pham Thi Quyen, Le Pham Tan Quoc","doi":"10.5564/mjc.v24i50.2853","DOIUrl":"https://doi.org/10.5564/mjc.v24i50.2853","url":null,"abstract":"Rosemary leaf essential oil (RoEO) is extracted using steam distillation. The aim of study is to determine physicochemical characteristics of essential oil (EO), such as acid/saponification/esterification index, relative/absolute density, freezing point, and fragrance retention. The chemical composition of EOs was analyzed by gas chromatography-mass spectrometry (GC-MS) method and identified 50 volatile compounds, of which α-Pinene (33.76%), 1,8-Cineole (18.47%), and Levoverbenone (6.11%) constituted the highest proportions in EO. The antioxidant capacity (AC) of the EO was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method with a half-maximum inhibitory concentration (IC50) of 425.473 mg/mL. In particular, antibacterial activity (AA) by the paper plate diffusion method for susceptibility testing to essential oil showed that RoEO strongly inhibited the growth of four tested bacterial strains (Staphylococcus aureus, Bacillus cereus, Salmonella typhimurium, and Escherichia coli). Perhaps, it is possible to apply RoEO in the food industry and other fields owing to the good properties of RoEO.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"62 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135316208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Narantsogt Natsagdorj, Narangarav Lkhagvasuren, B. Munkhjargal, J. Temuujin
Zeolites are a family of open-framework aluminosilicate minerals used in many diverse fields, including building materials, agriculture, water treatment, and catalysis. In this study, natural zeolites were mechano-chemically treated by co-milling with corundum and cristobalite. The idea behind the study was that co-milling with high-hardness oxides would cause natural zeolite to undergo more structural distortion, potentially increasing its reactivity and sorption capabilities. Corundum has a density of 3.95 g/cm3 and a hardness of 9, while cristobalite has a density of 2.27 g/cm3 and a hardness of 6-7, according to the Mohs hardness scale. In a planetary ball mill, the zeolites and 20 wt.% of various oxides were co-ground for 30 min. The grinding media used were hardened steel balls with a weight ratio of 20:1 between the balls and the minerals. Raw minerals and milled products were evaluated using X-ray diffraction, Fourier-transform infrared spectroscopy and scanning electron microscopy. It revealed that co-milling with different hardness oxides had a minor effect on the structural distortion of raw zeolite. Crystallite size reduction and amorphization were observed in high hardness oxides rather than in zeolite particles. After milling, the amorphization of natural zeolite milled alone was 30.4%, while no significant amorphization was observed when co-milled with corundum and cristobalite. Preliminary results of Cr(VI) adsorption tests on raw and milled zeolites indicate that co-milling with high-hardness oxides is not the preferred method to enhance the activity of natural zeolite.
{"title":"Influence of co-milling oxide physical properties on the structural changes of natural clinoptilolite zeolites","authors":"Narantsogt Natsagdorj, Narangarav Lkhagvasuren, B. Munkhjargal, J. Temuujin","doi":"10.5564/mjc.v24i50.1250","DOIUrl":"https://doi.org/10.5564/mjc.v24i50.1250","url":null,"abstract":"Zeolites are a family of open-framework aluminosilicate minerals used in many diverse fields, including building materials, agriculture, water treatment, and catalysis. In this study, natural zeolites were mechano-chemically treated by co-milling with corundum and cristobalite. The idea behind the study was that co-milling with high-hardness oxides would cause natural zeolite to undergo more structural distortion, potentially increasing its reactivity and sorption capabilities. Corundum has a density of 3.95 g/cm3 and a hardness of 9, while cristobalite has a density of 2.27 g/cm3 and a hardness of 6-7, according to the Mohs hardness scale. In a planetary ball mill, the zeolites and 20 wt.% of various oxides were co-ground for 30 min. The grinding media used were hardened steel balls with a weight ratio of 20:1 between the balls and the minerals. Raw minerals and milled products were evaluated using X-ray diffraction, Fourier-transform infrared spectroscopy and scanning electron microscopy. It revealed that co-milling with different hardness oxides had a minor effect on the structural distortion of raw zeolite. Crystallite size reduction and amorphization were observed in high hardness oxides rather than in zeolite particles. After milling, the amorphization of natural zeolite milled alone was 30.4%, while no significant amorphization was observed when co-milled with corundum and cristobalite. Preliminary results of Cr(VI) adsorption tests on raw and milled zeolites indicate that co-milling with high-hardness oxides is not the preferred method to enhance the activity of natural zeolite.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43925240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This research investigates the extraction of copper from copper-containing leaching residue, which includes 33.45% of copper, 14.14% of iron, 23.87% of sulfur and trace amounts of silver and other elements. Roasting the copper-containing residue under air and oxygen flow convert sulfides into sulfate, followed by water and acid leaching to extract copper. The process parameters, including leaching temperature, sulfuric acid concentration, leaching time, solid-to liquid ratio, and agitation speed, were optimized for both water and acid leaching methods. Results showed that the maximum copper dissolution efficiency was 93.12% with water leaching, and 97.16% with acid leaching. Chemical analysis revealed that the water and acid leaching residue contained 48.13% and 31.64% of iron, respectively. This study provides valuable insights into the process optimization for copper extraction from copper-containing leaching residue, which can inform the development of more efficient and sustainable methods for metal recovery.
{"title":"Treatment of copper-containing leaching residue by sulfation roasting followed by acid/water leaching","authors":"Nyamdelger Shirchinnamjil, Narangarav Tumen-Ulzii, Nemekhbayar Davaadorj, Khulan Byambasuren, Sarantsetseg Purevsuren, Ulziibadrakh Erdenebat, Enkhtuul Surenjav","doi":"10.5564/mjc.v24i50.1310","DOIUrl":"https://doi.org/10.5564/mjc.v24i50.1310","url":null,"abstract":"This research investigates the extraction of copper from copper-containing leaching residue, which includes 33.45% of copper, 14.14% of iron, 23.87% of sulfur and trace amounts of silver and other elements. Roasting the copper-containing residue under air and oxygen flow convert sulfides into sulfate, followed by water and acid leaching to extract copper. The process parameters, including leaching temperature, sulfuric acid concentration, leaching time, solid-to liquid ratio, and agitation speed, were optimized for both water and acid leaching methods. Results showed that the maximum copper dissolution efficiency was 93.12% with water leaching, and 97.16% with acid leaching. Chemical analysis revealed that the water and acid leaching residue contained 48.13% and 31.64% of iron, respectively. This study provides valuable insights into the process optimization for copper extraction from copper-containing leaching residue, which can inform the development of more efficient and sustainable methods for metal recovery.","PeriodicalId":36661,"journal":{"name":"Mongolian Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43642058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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