IgG4-Related Disease: A Concise Review

Carolyn Lee, C. To
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引用次数: 0

Abstract

IgG4-related disease (IgG4-RD) is a multi-organ fibroinflammatory disorder that may result in organ dysfunction and complications. Glucocorticoids remain the primary treatment for inducing remission, while recently reported disease phenotypes might inform personalized therapeutic strategies. Progress in understanding the pathophysiology of IgG4-RD has led to the identification of novel treatment targets. Ongoing research will further refine the optimal treatment for IgG4-RD. This review offers an update on the latest evidence on the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of IgG4-RD.
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IgG4相关疾病综述
igg4相关疾病(IgG4-RD)是一种多器官纤维炎性疾病,可导致器官功能障碍和并发症。糖皮质激素仍然是诱导缓解的主要治疗方法,而最近报道的疾病表型可能为个性化治疗策略提供信息。对IgG4-RD病理生理学的理解取得了进展,从而确定了新的治疗靶点。正在进行的研究将进一步完善IgG4-RD的最佳治疗方法。本文综述了IgG4-RD的流行病学、发病机制、临床特征、诊断和治疗方面的最新证据。
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自引率
0.00%
发文量
13
审稿时长
12 weeks
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