New Treatment New Complication – Mini Review

Á. Pethő
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Abstract

Nephrotoxicity caused by medication could limit the treatment success. In multiple malignancies are playing crucial role the anti-cancer drugs which have well known nephrotoxicity. Using the conventional chemotherapies acute kidney injury could develop but not in all patients who are suffering cancers. In these patients will acute tubulointerstitial nephritis or rarely nephrotic syndrome occur. The onco-pharmacology is an intensively investigated field. In the recent decade’s novel therapies founded. The new treatments in oncology have more targeted affect on cancer cells. These drugs will be modifying the whole immune system with the fine balance between cancer surveillance and preserving self-tolerance. The immune checkpoint inhibitors have superior anti-cancer therapeutic affect but new, until unknown complication raised. In this mini review we will discuss the most acute kidney injuries during chemotherapy.
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新治疗新并发症-迷你回顾
药物引起的肾毒性可能限制治疗的成功。在多种恶性肿瘤中,具有肾毒性的抗癌药物起着至关重要的作用。使用传统的化疗方法可能会导致急性肾损伤,但并不是所有的癌症患者都会出现急性肾损伤。这些患者会发生急性肾小管间质性肾炎或罕见的肾病综合征。肿瘤药理学是一个被广泛研究的领域。近十年来新疗法应运而生。肿瘤学的新疗法对癌细胞有更有针对性的作用。这些药物将改变整个免疫系统,在癌症监测和保持自我耐受性之间取得良好的平衡。免疫检查点抑制剂具有较好的抗癌治疗效果,但出现了新的未知并发症。在这篇简短的综述中,我们将讨论化疗期间最严重的肾损伤。
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