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Association Between Blood Flow Rate of Arteriovenous Access and Mortality in Prevalent Haemodialysis Patients: A Five-Year Prospective Study 流行血液透析患者动静脉通道血流量与死亡率的关系:一项为期五年的前瞻性研究
Pub Date : 2022-12-31 DOI: 10.36959/832/408
Roca-Tey Ramon, Roda Amparo, Ibrik Omar, Samon Rosa, González-Oliva Juna Carlos, Ugalde-Altamirano Jessica, Viladoms Jordi, Calls Jordi
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引用次数: 0
A Case of Severe Acute Hyperphosphatemia Secondary to Ingestion of Phosphoric Acid Solution Treated with Continuous Renal Replacement Therapy 连续肾替代疗法治疗继发于摄入磷酸溶液的严重急性高磷血症1例
Pub Date : 2022-12-31 DOI: 10.36959/832/409
Lee Pei Shan, B. Shashidhar, Mayank Chawla
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引用次数: 0
Considerations in the Management of Covid-19 in Patients with Chronic Kidney Disease 慢性肾病患者Covid-19治疗的注意事项
Pub Date : 2022-12-31 DOI: 10.36959/832/410
C. Joshua, Hasni Kamran, S. Hafiz
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引用次数: 0
NSAIDs, Dehydration and Acute Kidney Failure in the Young Adults: An Unrecognized Entity? 非甾体抗炎药、脱水和年轻人急性肾衰竭:一个未被认识的实体?
Pub Date : 2021-10-23 DOI: 10.36959/832/407
Czerlau Cecilia, Sidler Daniel, Vogt Bruno
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drug classes worldwide. As a side effect of the therapy can occur an acute interstitial nephritis (AIN) or an acute tubular necrosis (ATN). In acute kidney injury, a major challenge is to distinguish between underlying etiologies. For instance, there are no disease-specific therapies for acute tubular necrosis, whereas acute interstitial nephritis requires immunosuppressive therapy. The differentiation of the two diseases is very important, but unfortunately, they present clinically and laboratory similarly. Good biomarker for differential diagnosis is lacking. Often renal biopsy is required for diagnosis. Renal biopsy is often associated with side effects and cannot be performed in all patients. Therefore, it is very important to know the small differences of the two diseases. Enclosed we present three typical cases in which we diagnosed ATN based on the clinic, history, and laboratory findings.
非甾体抗炎药(NSAIDs)是世界上使用最广泛的药物之一。作为治疗的副作用可发生急性间质性肾炎(AIN)或急性肾小管坏死(ATN)。在急性肾损伤中,一个主要的挑战是区分潜在的病因。例如,急性肾小管坏死没有疾病特异性治疗,而急性间质性肾炎需要免疫抑制治疗。两种疾病的鉴别非常重要,但不幸的是,它们在临床和实验室中的表现相似。缺乏鉴别诊断的良好生物标志物。诊断时通常需要肾活检。肾活检常伴有副作用,不能对所有患者进行。因此,了解两种疾病的细微差别是非常重要的。根据临床、病史和实验室结果,我们提出了三个典型的ATN病例。
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引用次数: 0
Traumatic Urethrovaginal Fistula from Female Genital Mutilation Presenting as Bladder Outlet Obstruction: A Rare Case Report 女性生殖器切割致创伤性尿道阴道瘘,表现为膀胱出口梗阻:一例罕见病例报告
Pub Date : 2021-07-08 DOI: 10.33552/aun.2021.03.000553
A. Muhammad
Background Urethrovaginal fistula is an abnormal communication between urethra and vagina by an epithelialized tract. In girls the cause can be congenital or post traumatic. Female genital mutilation may be associated with urethrovaginal fistula and the predominant presentation is that of continuous urinary incontinence. Presentation with bladder outlet obstruction and inability to pass urine is rare. We report a 12-year old girl with traumatic urethro-vaginal fistula post female genital mutilation who presented with inability to pass urine and bladder outlet obstruction. Case report This is a 12-year old girl who presented with urethral bleeding and inability to pass urine following female genital mutilation. She had suprapubic cystostomy due to failed urethral catheterization. Micturating cystourethrogram revealed huge bladder with tight bladder neck. The haemogram, urine microscopy, electrolyte urea and creatinine were within normal limits. She had examination under anaesthesia which revealed urethrovaginal fistula and obliteration of the bladder neck. She had multilayer repair of the fistula via abdominoperineal approach. Urethral catheter was removed after 6 weeks. She developed nocturnal enuresis post operatively which was managed with tolterodine. Conclusion Urethrovaginal fistula from female genital mutilation may present with bladder outlet obstruction. Micturating cystogram may not be diagnostic. Examination under anaesthesia may be necessary for proper diagnosis. Abdominoperineal multilayer repair is associated with good outcome.
尿道阴道瘘是尿道和阴道之间通过上皮化的通道发生的异常交通。女孩的病因可能是先天性的或创伤后的。女性生殖器切割可能与尿道阴道瘘有关,主要表现为持续尿失禁。膀胱出口梗阻及不能排尿是罕见的。我们报告一个12岁的女孩创伤性尿道阴道瘘后女性生殖器切割谁提出无法通过尿液和膀胱出口阻塞。病例报告:这是一名12岁的女孩,在女性生殖器切割后出现尿道出血和无法排尿。由于导尿失败,她做了耻骨上膀胱造口术。排尿膀胱尿道造影显示膀胱巨大,膀胱颈紧致。血象、尿镜检、电解质尿素、肌酐均在正常范围内。她在麻醉下检查发现尿道阴道瘘和膀胱颈阻塞。她通过腹-会阴入路对瘘管进行了多层修复。6周后拔除导尿管。术后出现夜间遗尿,给予托特罗定治疗。结论女性外阴残割所致尿道阴道瘘可表现为膀胱出口梗阻。排尿膀胱造影可能不具有诊断价值。为了正确诊断,麻醉下的检查可能是必要的。腹部-会阴多层修复具有良好的预后。
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引用次数: 0
Pulmonary Hypertension from Cardiorenal Sequelae in an 18-Year-Old 46, XY Phenotypically Female Patient with Denys-Drash Syndrome: Case Report and Review of Literature 一例18岁46,XY型Denys-Drash综合征女性患者心肾后遗症肺动脉高压病例报告及文献复习
Pub Date : 2021-06-23 DOI: 10.33552/aun.2021.03.000552
Mouhamed Nashawi MD
Denys-Drash Syndrome (DDS) is a rare cause of end-stage renal disease (ESRD) stemming from genetic mutations in the Wilms’ tumor 1 (WT1) gene. Albeit uncommon, it and other congenital nephropathies (e.g., Frasier syndrome) may warrant a clinical workup of cardiovascular disease in symptomatic patients with cardiopulmonary deficits, as the latter is associated with renal dysfunction given the multifarious physiologic roles and nodes of action concerning the kidneys. These include not only serving as a site of neural and hormonal stimuli that affect systemic equilibrium, but the regulation of blood pressure and osmolality as well. The cardiorenal demise classically seen in later stages of chronic kidney disease (CKD) in relatively older adults may arise earlier in these patients. We report the case of an 18-year-old 46, XY phenotypic female with DDS who complained of increasingly nettlesome dyspnea. Initially, she presented with a low index of suspicion for diminished cardiopulmonary fitness. However, further clinical workup which included catheterization and cardiac imaging was significant for findings of pulmonary hypertension.
Denys-Drash综合征(DDS)是一种罕见的终末期肾脏疾病(ESRD),源于Wilms肿瘤1 (WT1)基因突变。尽管不常见,但它和其他先天性肾病(如弗雷泽综合征)可能需要对有心肺功能障碍症状的患者进行心血管疾病的临床检查,因为后者与肾功能障碍有关,因为肾脏有多种生理作用和作用节点。这些功能不仅包括作为影响系统平衡的神经和激素刺激的场所,还包括调节血压和渗透压。慢性肾脏疾病(CKD)晚期典型的心肾衰竭在相对较老的成年人中可能更早出现。我们报告一例18岁46,XY型女性与DDS谁抱怨越来越恼人的呼吸困难。最初,她表现出对心肺功能减退的低怀疑指数。然而,进一步的临床检查,包括导管检查和心脏成像,对于肺动脉高压的发现是重要的。
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引用次数: 0
Situs Inversus & Adult Polycystic Kidney Disease 成人多囊肾病
Pub Date : 2021-05-26 DOI: 10.33552/aun.2021.03.000551
M. Hashmi
Situs Inversus totalis is rare disorder in which there is transposition of organs position. Polycystic kidney disease is a disorder in which water containing cysts are formed in kidneys. Though named as polycystic kidney disease but cysts are formed in other organs such as liver, pancreas, seminal vesicles & arachnoid membrane. Association of these two conditions is rare.
全位倒置是一种罕见的器官位置移位的疾病。多囊肾病是一种在肾脏中形成含水囊肿的疾病。虽然被称为多囊肾病,但囊肿形成于其他器官,如肝脏、胰腺、精囊和蛛网膜。这两种情况的关联是罕见的。
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引用次数: 0
Effects of Different Doses of Oral Essential Amino Acid Supplementation in the Patients Aged over 80 Years on Chronic Hemodialysis 不同剂量口服必需氨基酸对80岁以上慢性血液透析患者的影响
Pub Date : 2021-05-16 DOI: 10.36959/832/406
S. Toru, Ono Tomoaki, Ono Takashi, Nagata Masaharu, Nakamura Yasuko, Iida Mikako, Fukumitsu Toma
The prevalence of malnutrition especially of essential amino acid (EAA) is a significant concern in end-stage renal disease (ESRD) and hemodialysis (HD) patients. The present study evaluates the efficacy of Amiyu® Granule (AG), a pharmaceutically manufactured oral EAA and histidine supplement, in the improvement of the nutritional indices of the ESRD and HD elderly patients (> 80-year-old).
在终末期肾病(ESRD)和血液透析(HD)患者中,营养不良特别是必需氨基酸(EAA)的患病率是一个重要的问题。本研究评价药用口服EAA和组氨酸补充剂阿米郁®颗粒剂(AG)对老年ESRD和HD(> 80岁)患者营养指标的改善效果。
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引用次数: 0
Knowledge about Benefits of Kidney Transplantation: A Survey of Dialysis Patients. 关于肾移植益处的知识:对透析患者的调查。
Pub Date : 2021-05-13 DOI: 10.33552/aun.2021.02.000550
Valerie Nwanji, Aria Ghahramani, Mujahed Dauleh, N. Ghahramani
BackgroundKnowledge about benefits of kidney transplantation (KT) is an important determinant of the patients' decision to pursue KT. We investigated factors associated with End Stage Renal Disease (ESRD) patients' knowledge about KT benefits.MethodsWe randomly invited 1,400 dialysis patients to complete a survey about benefits of KT. Using multivariate analysis, we calculated odds ratios for the probability of choosing the correct responses.ResultsOf 673 participants, 17.6% agreed with benefit of KT for older patients, 36.5% agreed with benefit of KT for diabetic patients, and 31.5% agreed with benefit of pre-emptive KT. Non-white (OR: 0.68) and older (OR: 0.65) participants were less likely to agree with the survival benefit of KT. Older participants were less likely to agree with benefit of KT for older (OR: 0.64), and diabetic patients (OR: 0.54). Participants with less than high school education were less likely to agree with benefit of pre-emptive KT (OR: 0.58). Participants with a previous KT were more likely to agree with benefit of KT for older (OR: 2.32), and diabetic patients (OR: 2.50), and with the benefit of pre-emptive KT (OR: 2.34). Participants who had received 3 or more modes of education about KT were more likely to agree with benefit of KT for diabetic patients (OR: 2.04), and with benefit of pre-emptive KT (OR:1.67).ConclusionsDialysis patients have limited knowledge about benefits of KT. Previous KT, exposure to 3 or more modes of KT education, and education attainment are significant contributors to knowledge about KT benefits.
背景:了解肾移植的益处是决定患者是否接受肾移植的重要因素。我们调查了与终末期肾病(ESRD)患者对KT益处的了解相关的因素。方法随机抽取1400例透析患者进行KT获益调查。使用多变量分析,我们计算了选择正确答案的概率的比值比。结果673名参与者中,17.6%的人同意老年患者的KT获益,36.5%的人同意糖尿病患者的KT获益,31.5%的人同意先发制人的KT获益。非白人(OR: 0.68)和老年(OR: 0.65)参与者不太可能同意KT的生存益处。年龄较大的参与者不太可能同意KT对老年人(OR: 0.64)和糖尿病患者(OR: 0.54)的益处。低于高中教育程度的参与者不太可能同意先发制人的KT的好处(OR: 0.58)。先前有KT的参与者更有可能同意老年人(OR: 2.32)和糖尿病患者(OR: 2.50)的KT的益处,以及先发制人的KT的益处(OR: 2.34)。接受过3种或以上KT教育模式的参与者更倾向于同意糖尿病患者KT的益处(or: 2.04)和先发制人KT的益处(or:1.67)。结论透析患者对KT的益处认识有限。有过KT经历、接受过3种或3种以上的KT教育模式以及受教育程度是影响KT收益的重要因素。
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引用次数: 2
Idiopathic Membranous Nephropathy at a Young Age 年轻时的特发性膜性肾病
Pub Date : 2021-05-07 DOI: 10.33552/aun.2021.02.000549
Muhammad Tanzeel Abbasi
Primary or idiopathic membranous nephropathy (MN) is distinctive and one of the most common causes of nephrotic syndrome in adults. It is quite prevalent in all races and has no gender predisposition. However, white adults are at more risk of MN. It is a relatively less common entity in pediatric population. We report a case of 12 years old female with idiopathic MN. She had no symptoms suggestive of nephrotic syndrome and was normotensive. She had incidental finding of proteinuria which was investigated, and renal biopsy revealed the features of MN.
原发性或特发性膜性肾病(MN)是独特的,也是成人肾病综合征最常见的原因之一。它在所有种族中都很普遍,没有性别易感性。然而,白人成年人患MN的风险更高。这是一个相对不常见的实体在儿科人群。我们报告一例12岁女性特发性MN。患者无肾病综合征症状,血压正常。她偶然发现蛋白尿,经检查,肾活检显示MN的特征。
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引用次数: 0
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Annals of urology & nephrology
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