Evaluation of phytochemical content, antioxidant, antimicrobial activity and DNA cleavage effect of endemic Linaria corifolia Desf. (Plantaginaceae)

M. Gul, Ilkay Ozturk Cali, A. Cansaran, Onder Idil, Irem Kulu, Umut Çelikoğlu
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引用次数: 11

Abstract

Abstract The aim of this study is to isolate Linaria corifolia Desf. (Plantaginaceae) and identify new apigenine derivatives 6,3′-dimethoxyapigenin-7-O-[(rhamnosyl)-(1–2)-6″-acetyl glucoside]. Moreover, we analyzed biological activity and flavonoids by using HPLC methods from extracts. The L. corifolia Desf. samples were collected in Black Sea Region of Turkey. Ethanol (EtOH), ethyl acetate (EtOAc) and dichloromethane (DCM) extracts in aerial and under solid parts of plant were evaluated for antioxidant, antimicrobial activity and effect of DNA cleavage. Quercetin, gallic acid and catechin as flavonoids were identified in EtOH, EtOAc, DCM extracts.
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地方特有的卷叶Linaria corifolia Desf.植物化学成分、抗氧化、抗菌活性和DNA裂解作用的评价。(车前草科)
摘要本研究的目的是分离香茅。(车前草科),并鉴定了新的芹菜素衍生物6,3′-二甲氧基芹菜素-7-O-[(鼠李糖基)-(1-2)-6〃-乙酰基葡糖苷]。此外,采用高效液相色谱法对提取物的生物活性和黄酮类化合物进行了分析。香叶L.corifolia Desf。样本采集于土耳其黑海地区。对植物地上和固体下部分的乙醇(EtOH)、乙酸乙酯(EtOAc)和二氯甲烷(DCM)提取物的抗氧化、抗菌活性和DNA切割效果进行了评估。在EtOH、EtOAc和DCM提取物中鉴定出槲皮素、没食子酸和儿茶素为黄酮类化合物。
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Cogent Chemistry
Cogent Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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