Design of 3D smart scaffolds using natural, synthetic and hybrid derived polymers for skin regenerative applications

Q1 Engineering Smart Materials in Medicine Pub Date : 2023-01-01 DOI:10.1016/j.smaim.2022.09.005
Laldinthari Suamte, Akriti Tirkey, Punuri Jayasekhar Babu
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引用次数: 24

Abstract

Effective wound care is a major concern as many conventional wound healing methods and materials have failed in facilitating proper healing, instead disrupts the overall healing process, leading to the development of chronic wounds. Advancement in tissue engineering has led to the development of scaffolds; a 3D construct which can be utilized as a template for cell growth and regeneration while preventing infection along with acceleration of the wound healing process. Natural and synthetic polymers are used extensively for scaffold production and hybrid scaffolds are also introduced which constitutes a combination of natural and synthetic polymers. This review highlights the design of scaffolds using different kinds of polymers for skin tissue engineering.

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使用天然、合成和混合衍生聚合物设计用于皮肤再生应用的3D智能支架
有效的伤口护理是一个主要问题,因为许多传统的伤口愈合方法和材料在促进适当愈合方面失败了,相反,破坏了整体愈合过程,导致慢性伤口的发展。组织工程的进步导致了支架的发展;这是一种3D结构,可以用作细胞生长和再生的模板,同时防止感染,加速伤口愈合过程。天然聚合物和合成聚合物被广泛用于支架的生产,同时也介绍了由天然聚合物和合成聚合物组成的杂化支架。本文综述了不同类型聚合物用于皮肤组织工程支架的设计。
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来源期刊
Smart Materials in Medicine
Smart Materials in Medicine Engineering-Biomedical Engineering
CiteScore
14.00
自引率
0.00%
发文量
41
审稿时长
48 days
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