Cytotoxic phenolic constituents from the leaves of Ehretia asperula

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY Bangladesh Journal of Pharmacology Pub Date : 2019-12-15 DOI:10.3329/bjp.v14i4.42414

Dang Dinh Kim, Vu Thi Nguyet, Ha Xuan Anh, N. Trang, Nguyen Hong Chuyen, L. Huong, Tran Thị Hong Ha, D. H. Ho, N. Dat

引用次数: 2

Abstract

Compound 1: 4-hydroxy-3-[4-(2-hydroxyethyl)-phenoxy]-benzaldehyde HR-ESI-MS: m/z 259.0975 [M+H]+ (calcld. 259.0970 for C15H15O4). 1H-NMR (500 MHz, CD3OD): δH 9.71 (1H, s, H-7), 7.34 (1H, dd, J = 8.0, 2.0 Hz, H-6), 7.32 (1H, d, J = 2.0 Hz, H-2), 7.15 (2H, d, J = 8.0 Hz, H-3′, 5′), 7.04 (1H, d, J = 8.0 Hz, H-5), 6.84 (2H, d, J = 8.0 Hz, H-2′, 6′), 3.71 (2H, t, J = 7.0 Hz, H-8′), 2.73 (2H, t, J = 7.0 Hz, H-7′). 13C-NMR (125 MHz. CD3OD): δC 131.1 (C, C-1), 118.3 (CH, C-2), 147.2 (C, C-3), 151.8 (C, C-4), 116.1 (CH, C5), 128.8 (CH, C-6), 158.5 (C, C-1′), 119.5 (CH, C-2′, 6′), 131.0 (CH, C-3′, 5′), 133.7 (C, C4′), 193.1 (CH, C-7), 39.4 (CH2, C-7′), 64.0 (CH2, C-8′).

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黑藤叶的细胞毒性酚类成分

化合物1:4-羟基-3-[4-（2-羟乙基）-苯氧基]-苯甲醛HR-ESI-MS:m/z 259.0975[m+H]+（C15H15O4的计算值259.0970）。1H-NMR（500 MHz，CD3OD）：δH 9.71（1H，s，H-7。13C-NMR（125 MHz.CD3OD）：δC 131.1（C，C-1）、118.3（CH，C-2）、147.2（C，C-3）、151.8（C，C-4）、116.1（CH，C5）、128.8（CH，C-6）、158.5（C，C-1′）、119.5（CH，C-2′，6′）、131.0（CH，C-3′，5′）、133.7（C，C4′）、193.1（CH、C-7）、39.4（CH2，C-7′）、64.0（CH2、C-8′）。

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来源期刊

Bangladesh Journal of Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

1.50

自引率

18.80%

发文量

审稿时长

>12 weeks

期刊介绍： Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS). A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements. Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review. Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.