The Patent Fact about Alcohol and Getting Stroke: A Case Control Study

K. H. Patel, S. Gandhi, Dhruti Vaidya
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Abstract

Introduction: Globally 17.9 million people die each year from CVDs (Cardio Vascular Diseases) and 85% of all CVD deaths are due to heart attacks and strokes. According to the World Health Organization (WHO), 15 million people worldwide suffer from stroke every year and after ischemic heart disease, stroke is the second most leading cause of death. Objective: To study alcohol consumption as a risk factor in patients with acute strokes. Method: Case control study was conducted among 148 newly diagnosed cases of CT scan / MRI-confirmed stroke and 148 non-stroke controls attending the tertiary hospital of central Gujarat. Sample size calculation was done, assuming the power ratio of the number of controls same as numbers of cases i.e.,1:1, specifying values for two-sided confidence level=95% (error=5%), power of study=80%, odd ratio=2.15, percent of cases with exposure=82% and percent of controls with exposure=68%. Patients who are willing to participate in the study were included. The data were analyzed using the EPI INFO TM 7.0.8.0 software. Results: Out of the total 148 cases, 100 (67.56 per cent) were male and 48 (32.43 per cent) were female. The odds of getting stroke among alcoholic was two times more as compared to non-alcoholic patients. Heavy alcohol drinkers have a significant association. Conclusion: According to the study results male married patients who drank heavily had a higher risk of stroke than light/moderate alcoholics.
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关于酒精与中风的专利事实:一项病例对照研究
导言:全球每年有1790万人死于心血管疾病(CVD), 85%的CVD死亡是由于心脏病发作和中风。根据世界卫生组织(世卫组织)的数据,全世界每年有1500万人患中风,中风是仅次于缺血性心脏病的第二大死因。目的:研究急性脑卒中患者饮酒的危险因素。方法:对在古吉拉特邦中部三级医院就诊的148例CT扫描/ mri确诊的脑卒中新诊断病例和148例非脑卒中对照进行病例对照研究。进行样本量计算,假设对照数与病例数的功率比相同,即1:1,指定双侧置信水平=95%(误差=5%),研究功率=80%,奇数比=2.15,暴露病例百分比=82%,暴露对照组百分比=68%。愿意参加这项研究的患者被纳入研究对象。采用EPI INFO TM 7.0.8.0软件对数据进行分析。结果:148例患者中,男性100例(67.56%),女性48例(32.43%)。酗酒者患中风的几率是非酗酒者的两倍。重度饮酒者有明显的关联。结论:根据研究结果,重度饮酒的已婚男性患者中风的风险高于轻度/中度饮酒者。
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发文量
17
审稿时长
12 weeks
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