{"title":"Evaluation of the anticancer effects induced by cold atmospheric plasma on leukemia stem cells","authors":"Rui Feng, Ning Ning, Miao Tian, Sansan Peng, Shuai Wang, Bing Li, Hao Zhang, Dehui Xu","doi":"10.1088/2516-1067/ab9154","DOIUrl":null,"url":null,"abstract":"The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.","PeriodicalId":36295,"journal":{"name":"Plasma Research Express","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/2516-1067/ab9154","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasma Research Express","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/2516-1067/ab9154","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 1
Abstract
The application of cold atmospheric plasma (CAP) in cancer treatment has received extensive attention. However, little research was observed on the anticancer effects of CAP to tumor stem cells. Here, we analyzed the discharge characteristics of a CAP jet and plasma-induced effects on acute myeloid leukemia (AML) stem cells. Our results showed that the most active particles can be produced when helium is doped with 0.5% oxygen and the jet device is driven by a pulsed power supply. And when using this plasma jet device to treat acute myeloid leukemia (AML) stem cells, it is found that CAP jet can effectively inhibit the cell activity of AML stem cells, which provides new ideas for the treatment of AML.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
