Opioid Free Anesthesia with Goal-Directed Strategies Based On Monitoring For Spine Surgery in a Patient with Opioid Intolerance: A Case Report

Marco Dornelles, Larissa P. Dornelles
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Abstract

This study aimed to report the use of a multimodal anesthetic (MA) regimen by combining a panoply of drugs without opioids for posterior spinal fusion surgery in a patient with Low-back incapacity and opioid intolerance. The surgery occurred without incidents nor do hemodynamic instabilities, except for a delay in waking up, reverse with extra doses of decurarizing. On the 13th day, she reported mild pain (VAS 2/10) and was satisfied with the result of the surgery. This case report highlights the new concept of using manifold drugs through the use a goal-direct strategies based on monitoring. Furthermore, we emphasize the use of good monitoring, such as ANI and IGP, for the success of this type of surgery. Scale; LIF: Lumbar Interbody Fusion; ALIF: Anterior Lumbar Interbody Fusion; PLIF: Posterior Lumbar Interbody Fusion; ERAS: Enhanced Recovery After Surgery; ANS: Autonomic Nervous System; OFA: Opioid-Free Anesthesia; BIS: Bispectral Index; TOF: Train-Of-Four; ANI: Analgesia Nociception Index; ICG: Impedance Cardiography; SV: Systolic Volume; HR: Heart Rate; CO: Cardiac Output; VET: Ventricular Ejection Time; MAC: Minimum Alveolar Concentration; PACU: Post-anesthesia Care Unit; AHT: Arterial Hypertension; CNS: Central Nervous System.
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基于阿片类药物不耐受患者脊柱手术监测的无阿片类药物麻醉目标导向策略:一例报告
本研究旨在报告在一名下背部功能障碍和阿片类药物不耐受的患者中,通过联合一系列不含阿片类的药物进行脊柱融合术,使用多模式麻醉(MA)方案。手术没有发生任何事件,血液动力学不稳定也没有发生,除了苏醒延迟,通过额外剂量的去尿酸来逆转。第13天,她报告轻微疼痛(VAS 2/10),并对手术结果感到满意。本案例报告强调了通过使用基于监测的目标直接策略来使用多种药物的新概念。此外,我们强调使用良好的监测,如ANI和IGP,以确保此类手术的成功。规模LIF:腰椎间融合术;ALIF:腰椎前路椎间融合术;PLIF:腰椎融合术;ERAS:增强术后恢复;自主神经系统;OFA:无阿片类药物麻醉;BIS:双谱指数;TOF:四列;ANI:镇痛镇痛指数;ICG:阻抗心脏描记术;SV:收缩容积;HR:心率;CO:心输出量;VET:心室射血时间;MAC:最小肺泡浓度;PACU:麻醉后护理室;AHT:动脉性高血压;中枢神经系统。
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