Sero-epidemiology of Plasmodium vivax infection among Sudanese's and Ethiopians in Khartoum State

Abstract

Plasmodium vivax is a hemo-pathogenic parasite that belongs for the phylum Apicomplexa. It causes malaria which is the public health significant. Most of the research and published literature on malaria focuses on Plasmodium falciparum and much less on Plasmodium vivax.1 This focus is due to the very high burden of mortality attributed to the falciparum species in Africa.2 However, there is growing evidence that Plasmodium vivax is responsible for a significant burden of disease worldwide accounting for half of all malaria cases in Asia and Latin America, will nearly 2.5 billion people at risk of infection.3 All species are transmitted by the bite of an infective female Anopheles mosquitoes control and management of vivax malaria is difficult, and the present particular challenges.4 Hematological changes that have been reported to accompany malaria are anemia, thrombocytopenia, leucopenia, atypical lymphocytosis, and infrequently disseminated intravascular coagulation.5 Some studies have shown that Plasmodium vivax can also cause severe disease and the hematological parameters are usually changed in such cases. The present study was undertaken to assess the hematological alterations in vivax malaria patients in comparison between Sudanese and Ethiopians.6