Effect and safety of radiotherapy post operation combined with hyperbaric oxygen in treatment of keloid

中华医学美学美容杂志 Pub Date : 2019-06-15 DOI:10.3760/CMA.J.ISSN.1671-0290.2019.03.018

Guo Dazhi, Wei Shi, Zhang Dunxiao, Youbin Wang, Pan Shu-yi

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引用次数: 1

Abstract

Objective To explore the effect and safety of radiotherapy post operation combined with hyperbaric oxygen in treatment of keloid. Methods From Jan. 1st 2015 to Dec. 30th 2016, patients with keloid in Plastic Surgery Hospital of Beijing Union Medical College and Navy General Hospital were selected and randomly divided into the radiotherapy post operation group and radiotherapy post operation combined with hyperbaric oxygen group. Adverse reactions of both groups of patients during treatment were recorded and calculated. The Vancouver scar scale was used to evaluate treatment effect of both groups of patients; The clinical effect and the recurrence rate of both groups were observed. Results Compared with before treatment, the Vancouver scar scale scores of both groups of patients after treatment was decreased significantly, but patients in radiotherapy post operation combined with hyperbaric oxygen gorup decreased more significantly (P 0.05). Conclusions Radiotherapy post operative combined with hyperbaric oxygen in the treatment of keloids is better than postoperative radiotherapy alone, with low recurrence rate and good safety. It may become a new choice for keloid treatment. Key words: Keloid; Surgery; Safety; Treatment Outcome; Radiotherapy; Hyperbaric Oxygen Treatment

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术后放疗联合高压氧治疗瘢痕疙瘩的疗效及安全性

目的探讨术后放疗联合高压氧治疗瘢痕疙瘩的疗效及安全性。方法选取2015年1月1日至2016年12月30日在北京协和医学院整形外科医院和海军总医院就诊的瘢痕疙瘩患者，随机分为放疗术后组和放疗术后联合高压氧组。记录并计算两组患者在治疗过程中的不良反应。采用温哥华疤痕量表评价两组患者的治疗效果;观察两组患者的临床疗效及复发率。结果与治疗前比较，治疗后两组患者温哥华疤痕评分均显著下降，但术后放疗联合高压氧组患者下降更为显著(P < 0.05)。结论术后放疗联合高压氧治疗瘢痕疙瘩优于术后单纯放疗，复发率低，安全性好。它可能成为治疗瘢痕疙瘩的新选择。关键词:瘢痕疙瘩;手术;安全;治疗效果;放射治疗;高压氧治疗

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来源期刊

中华医学美学美容杂志

自引率

0.00%

发文量

4641

期刊介绍： "Chinese Journal of Medical Aesthetics and Cosmetology" is a high-end academic journal focusing on the basic theoretical research and clinical application of medical aesthetics and cosmetology. In March 2002, it was included in the statistical source journals of Chinese scientific and technological papers of the Ministry of Science and Technology, and has been included in the full-text retrieval system of "China Journal Network", "Chinese Academic Journals (CD-ROM Edition)" and "China Academic Journals Comprehensive Evaluation Database". Publishes research and applications in cosmetic surgery, cosmetic dermatology, cosmetic dentistry, cosmetic internal medicine, physical cosmetology, drug cosmetology, traditional Chinese medicine cosmetology and beauty care. Columns include: clinical treatises, experimental research, medical aesthetics, experience summaries, case reports, technological innovations, reviews, lectures, etc.