Risk factors analysis of ischemic cerebrovascular disease combined with restless legs syndrome

Abstract

Objective To explore the risk factors for restless legs syndromes (RLS) in patients with ischemic cerebrovascular disease (ICVD).  Methods There were 370 patients with ICVD, 45 cases were combined with RLS (RLS group) and 325 cases were not combined with RLS (non-RLS group). The general clinical data [sex, age, body mass index (BMI), education, nationality, occupation, lifestyle, physical exercise, medical history, history of gestation and age of menopause in female] were recorded, and related chemical examinations [white cell count (WBC), hemoglobin (Hb), serum creatinine (Cr), blood urea nitrogen (BUN), fasting blood glucose, serum lipid, plasma homocysteine (Hcy), serum iron] were performed.  Results Compared with non-RLS group, BMI of patients in RLS group was higher ( t = 2.457, P = 0.014), Hb ( t = 2.819, P = 0.005) and serum iron ( t = 2.168, P = 0.024) were lower. Multivariate forward Logistic regression analysis showed that low Hb ( OR = 1.049, 95%CI: 1.017-1.082; P = 0.002) and serum iron ( OR = 1.121, 95% CI: 1.002-1.254; P = 0.047) were the risk factors for ICVD combined with RLS patients.  Conclusions RLS is common among patients with ICVD, and they have low Hb and serum iron levels. DOI: 10.3969/j.issn.1672-6731.2017.10.008