Assessment of Risk Factors for Severe Coronavirus Disease -19 in Taif Province, Saudi Arabia

Nuha A. Abdelmutalab
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Abstract

Coronavirus 2019 (COVID 19) is one of the pandemics registered for 2020, with the entire world affected. COVID 19 disease is diagnosed based on symptoms and risk factors, and both swab and RT-PCR tests are available to confirm the disease. The aim of this study was to the underlying health issues which might be connected to development of severe COVID19.A retrospective study was carried out in a tertiary hospital (Corona center) in Saudi Arabia from August 2020 to December 2020 to identify the risk factors of mortality in ICU admitted COVID-19 patients and to assess the underlining sociodemographic and medical conditions that may lead to the development of severe COVID-19. Data was collected from patients' medical records. In this study, 174 subjects were recruited and 71.3% of the population is male and 28.7% as female. Survival was 52%, whereas non-survivors was 48%. The average age was 57.7±16.0 years old. The most common clinical manifestations were shortness of breath (75.9%), cough (67.8%), and fever (64.9%). T2DM was one of the highest co-morbidities was documented. Binary logistic regression analysis confirmed both the age and fever showed the positive association (p<0.05) and the serum parameters such as CRP, d dimer, neutrophils and lymphocytes showed the elevated levels and positive association (p<0.05). In conclusion, the current study results confirmed HTN, CKD, and heart disease comorbidities all played a substantial impact in the development of COVID-19, and that older age (>60 years) also played a role in COVID 19 patients. Saudi Arabia is one of the nations that has successfully managed the COVID 19.
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沙特阿拉伯塔伊夫省严重冠状病毒病-19危险因素评估
2019冠状病毒(COVID 19)是2020年登记的流行病之一,全世界都受到影响。COVID 19疾病是根据症状和风险因素诊断的,可以通过拭子和RT-PCR检测来确认该疾病。这项研究的目的是探讨可能与严重COVID-19发展有关的潜在健康问题。2020年8月至2020年12月,在沙特阿拉伯的一家三级医院(科罗纳中心)进行了一项回顾性研究,以确定入住ICU的COVID-19]患者的死亡风险因素,并评估可能出现的突出社会人口统计学和医学状况导致严重新冠肺炎的发展。数据是从患者的医疗记录中收集的。在这项研究中,招募了174名受试者,71.3%的受试者为男性,28.7%为女性。存活率为52%,而非存活率为48%。平均年龄57.7±16.0岁。最常见的临床表现是呼吸急促(75.9%)、咳嗽(67.8%)和发烧(64.9%)。T2DM是最高的合并症之一。二元逻辑回归分析证实,年龄和发烧均显示正相关(p60岁)也在COVID 19患者中发挥作用。沙特阿拉伯是成功控制新冠肺炎疫情的国家之一。
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Bioscience Biotechnology Research Communications
Bioscience Biotechnology Research Communications BIOTECHNOLOGY & APPLIED MICROBIOLOGY-
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