{"title":"Organocatalysis: An overview on its application in oxidation and reduction reactions","authors":"Rammyani Pal, C. Mukhopadhyay","doi":"10.2174/2213337208666210719101409","DOIUrl":null,"url":null,"abstract":"\n\nOrganocatalysis has been established to be a wide-applicable approach from its inception and rediscovery in 2000. Proline was used as a catalyst in aldol condensation and soon after the successful emergence of iminium catalyzed reactions in organic synthesis. The development of new potential catalytic systems is always an essential and uphill task for scientists and researchers. The fundamental organic synthesis majorly deals with metal-based catalysts, whereas there is a constant surge of developing metal-free reaction conditions to make the reactions environmental friendly. For the synthesis of complex organic molecules, reduction and oxidation reactions are always needed, and there are plenty of catalysts available for these reactions. Organocatalysts are also developed and applied for these two elementary reactions. This review focuses on some of the latest developments and applications of organocatalystsin oxidation and reduction reactions in fundamental organic synthesis.\n","PeriodicalId":10945,"journal":{"name":"Current Organocatalysis","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Organocatalysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2213337208666210719101409","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 1
Abstract
Organocatalysis has been established to be a wide-applicable approach from its inception and rediscovery in 2000. Proline was used as a catalyst in aldol condensation and soon after the successful emergence of iminium catalyzed reactions in organic synthesis. The development of new potential catalytic systems is always an essential and uphill task for scientists and researchers. The fundamental organic synthesis majorly deals with metal-based catalysts, whereas there is a constant surge of developing metal-free reaction conditions to make the reactions environmental friendly. For the synthesis of complex organic molecules, reduction and oxidation reactions are always needed, and there are plenty of catalysts available for these reactions. Organocatalysts are also developed and applied for these two elementary reactions. This review focuses on some of the latest developments and applications of organocatalystsin oxidation and reduction reactions in fundamental organic synthesis.
期刊介绍:
Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.