A Rare Case of Extensive Spondylodiscitis

S. Nicolau, M. Moniz, J. Jardim, M. Grego
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Abstract

A 71-year-old man with a history of diabetes mellitus was admitted to our hospital with a 2-week history of fever and low back pain. Physical examination showed fever (38.1°C), painful palpation of the lower lumbar vertebrae and right lower limb paresis. Blood examination revealed an increased white blood cell count (16700x109/L) and C- reactive protein (22,39 mg/dL). Magnetic resonance imaging showed extensive spondylodiscitis, with osteomyelitis of the L5, S1 and S2 vertebral bodies, discitis, large epidural empyema, paraspinal and epidural abscesses. Patient was submitted to surgical treatment and was started on empirical antimicrobial therapy. Blood and intraoperative cultures were negative. Brucellosis and tuberculosis testing was negative. A 10- week course of antimicrobial therapy was performed with progressive decline of acute-phase reactants, reduction in pain and improvement of the neurological deficit. At 1-year follow up with light residual lower back pain and no neurological deficit.
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一例罕见的广泛性脊柱炎
一位有糖尿病病史的71岁男性因发烧和腰痛两周而入院。体格检查显示发热(38.1°C),下腰椎触诊疼痛,右下肢轻瘫。血液检查显示白细胞计数(16700x109/L)和C反应蛋白(22,39mg/dL)增加。磁共振成像显示广泛的椎间盘炎,伴有L5、S1和S2椎体骨髓炎、椎间盘炎、硬膜外大脓胸、椎管旁和硬膜外脓肿。患者接受手术治疗,并开始接受经验性抗菌治疗。血液和术中培养均为阴性。布鲁氏菌病和结核病检测均为阴性。进行为期10周的抗菌治疗,急性期反应物逐渐减少,疼痛减轻,神经功能缺损得到改善。随访1年,轻度残余下背痛,无神经功能缺损。
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