The effect of vitamin D deficiency on glycemic control in patients with type 2 diabetes mellitus

IF 0.2 Q4 HEALTH CARE SCIENCES & SERVICES Healthcare in Lowresource Settings Pub Date : 2023-06-08 DOI:10.4081/hls.2023.11340
Neveen Rashad Mostafa, Abeer Ahmed Mohamed Ali, R. Marzo
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Abstract

Multiple factors are involved in the development of type 2 diabetes mellitus (T2DM), but an imbalance between free radical formation and antioxidant removal is the main cause of diabetic complications. Micronutrients with antioxidant properties may have a role in the development of diabetes mellitus (DM) and its complications. Vitamin D has recently been found to have membrane antioxidant effect and a relationship to the development of T2DM, as it can modify its risk. Whether vitamin D deficiency has an effect on hyperglycemia in diabetic patients or not need further study. Our aim was to examine the effect of vitamin D deficiency on glycemic control in T2DM. We examined the vitamin D levels of 100 patients with T2DM and correlated them with fasting blood sugar and glycated hemoglobin A1c (HbA1c) levels. High levels of fasting blood sugar and HbA1c levels were significantly associated with vitamin D deficiency. Vitamin D deficiency negatively affects glycemic control in patients with T2DM.
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维生素D缺乏对2型糖尿病患者血糖控制的影响
2型糖尿病(T2DM)的发展涉及多种因素,但自由基形成和抗氧化剂去除之间的不平衡是糖尿病并发症的主要原因。具有抗氧化特性的微量营养素可能在糖尿病及其并发症的发展中发挥作用。维生素D最近被发现具有膜抗氧化作用,并与T2DM的发展有关,因为它可以改变其风险。维生素D缺乏是否对糖尿病患者的高血糖有影响需要进一步研究。我们的目的是研究维生素D缺乏对T2DM血糖控制的影响。我们检测了100名T2DM患者的维生素D水平,并将其与空腹血糖和糖化血红蛋白A1c(HbA1c)水平相关联。高水平的空腹血糖和HbA1c水平与维生素D缺乏显著相关。维生素D缺乏会对T2DM患者的血糖控制产生负面影响。
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来源期刊
CiteScore
0.10
自引率
0.00%
发文量
13
审稿时长
10 weeks
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