Maternal determinants of gestation length in the rhesus monkey.

Christopher L Coe, Gabriele R Lubach
{"title":"Maternal determinants of gestation length in the rhesus monkey.","authors":"Christopher L Coe, Gabriele R Lubach","doi":"10.31300/tdb.14.2021.63-72","DOIUrl":null,"url":null,"abstract":"<p><p>A gestation length of normal duration and natural delivery at term are considered to be important indicators of a healthy pregnancy, especially given the potentially adverse consequences for neonates of being born premature. While many have assessed the factors influencing gestation length in humans, and there has been considerable interest in the pregnancy duration of domesticated farm animals, this topic has not been re-assessed recently in rhesus monkeys, the most commonly used primate in biomedical research. In older articles, it's gestation length was typically reported to be 165 days, although most authors acknowledged that viable pregnancies could occur out to 180 days. Predicting the normal range of acceptable due dates has important veterinary implications for when to intervene in a prolonged pregnancy. Using archival records from a large, established breeding program, gestation lengths and infant birthweights were analyzed for 408 pregnancies across a 25-year period. The potential influence of maternal factors, including age and parity, was assessed. Familial concordance in gestation length within mother-daughter matrilines was examined, as well as similarity in length across repeat pregnancies for 84 multiparous females. Mean duration from mating to delivery was 168.8 days, longer than reported in most but not all previous articles. Many females birthed successfully at a longer duration that might have prompted consideration of a caesarian delivery. Gestation length for an individual female was fairly stable and significantly correlated across multiple pregnancies. There was not a pronounced transgenerational influence on gestation length even though familial propensities for birthing small and large infants were evident in the female descendants. Typical pregnancy lengths and birthweights are provided as reference norms to assist other breeding programs and to enhance our understanding of the natural reproduction of rhesus macaques that still live in many forested and urban locations across South Asia.</p>","PeriodicalId":75257,"journal":{"name":"Trends in developmental biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012481/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in developmental biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31300/tdb.14.2021.63-72","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

A gestation length of normal duration and natural delivery at term are considered to be important indicators of a healthy pregnancy, especially given the potentially adverse consequences for neonates of being born premature. While many have assessed the factors influencing gestation length in humans, and there has been considerable interest in the pregnancy duration of domesticated farm animals, this topic has not been re-assessed recently in rhesus monkeys, the most commonly used primate in biomedical research. In older articles, it's gestation length was typically reported to be 165 days, although most authors acknowledged that viable pregnancies could occur out to 180 days. Predicting the normal range of acceptable due dates has important veterinary implications for when to intervene in a prolonged pregnancy. Using archival records from a large, established breeding program, gestation lengths and infant birthweights were analyzed for 408 pregnancies across a 25-year period. The potential influence of maternal factors, including age and parity, was assessed. Familial concordance in gestation length within mother-daughter matrilines was examined, as well as similarity in length across repeat pregnancies for 84 multiparous females. Mean duration from mating to delivery was 168.8 days, longer than reported in most but not all previous articles. Many females birthed successfully at a longer duration that might have prompted consideration of a caesarian delivery. Gestation length for an individual female was fairly stable and significantly correlated across multiple pregnancies. There was not a pronounced transgenerational influence on gestation length even though familial propensities for birthing small and large infants were evident in the female descendants. Typical pregnancy lengths and birthweights are provided as reference norms to assist other breeding programs and to enhance our understanding of the natural reproduction of rhesus macaques that still live in many forested and urban locations across South Asia.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
恒河猴妊娠期长短的母体决定因素。
正常妊娠期长度和足月自然分娩被认为是健康妊娠的重要指标,特别是考虑到早产可能对新生儿造成的不利后果。虽然许多人已经评估了影响人类妊娠期长度的因素,并且对家养农场动物的妊娠期也有相当大的兴趣,但这一主题最近尚未在恒河猴(生物医学研究中最常用的灵长类动物)中重新评估。在较早的文章中,它的妊娠期通常为165天,尽管大多数作者承认,可怀孕的时间可能长达180天。预测正常范围的可接受的预产期有重要的兽医意义,何时干预延长妊娠。利用一个大型的、已建立的育种项目的档案记录,研究人员分析了25年来408次怀孕的妊娠长度和婴儿出生体重。评估了产妇因素(包括年龄和胎次)的潜在影响。研究了84例多胞胎女性的妊娠长度的家族一致性,以及重复妊娠的长度相似性。从交配到分娩的平均持续时间为168.8天,比之前大多数文章报道的要长,但不是全部。许多雌性在较长时间内成功分娩,这可能促使人们考虑剖腹产。单个雌性的妊娠期长度相当稳定,并且在多胎妊娠中显著相关。没有明显的跨代影响妊娠长度,即使家庭倾向生育小婴儿和大婴儿在女性后代中是明显的。典型的怀孕长度和出生体重作为参考标准,以协助其他育种计划,并加强我们对仍然生活在南亚许多森林和城市地区的恒河猴自然繁殖的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Epigenetic modulation of cell fate during pancreas development. Simplifying cell fate map by determining lineage history of core pathway activation during fate specification. Mouse zona pellucida proteins as receptors for binding of sperm to eggs. Developmental effects of in utero metformin exposure. Maternal determinants of gestation length in the rhesus monkey.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1