An Epidemiological Investigation of the Diphtheria Outbreaks Reported in a District of Gujarat

Harsh D. Shah, J. Patel, Aniket Rana, A. Sinha, M. Fancy
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Abstract

Introduction: Mortality and morbidity due to infectious disease have got reduced in the last couple of decades. Diphtheria is one of the infectious diseases which can be preventable with a complete immunization. Objective: To understand trends and identify factors affecting the outbreak of diphtheria in Banaskantha district of Gujarat. Method: A retrospective study based on the available case records for the years 2019, 2020 and 2021(till June). The study was conducted after the reported diphtheria cases in a district. The study was a public health response and intended to provide specific geographical recommendations to the district. The data was recorded from the reported case record and immunization registers. The data were analyzed for defined variables. Results: Out of the 366 cases identified during years 2019-2021.Almost 74% cases have occurred during 2019, with a 7.7% mortality rate. Total 48% of cases were among the age group of 5-10 years, with an increasing number of cases during August-December with specific geographical distribution. Among all the cases, 164 (44.5%) have never taken any vaccine in their lifetime or are unaware of the vaccination status, and 87.9% of cases have not taken third dose of DPT or Pentavalent Vaccine, which is associated statistically with the mortality. Conclusion: The prevalence of diphtheria cases was high in children who have not taken all three doses of DPT or Pentavalent vaccine. These have shown an essential role of immunization, focusing on the vaccine for all doses and need to create a customized awareness communication plan.
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古吉拉特邦某地区报告的白喉暴发流行病学调查
在过去的几十年里,传染病的死亡率和发病率已经降低了。白喉是一种可以通过全面免疫预防的传染病。目的:了解古吉拉特邦巴纳斯坎塔地区白喉疫情的流行趋势和影响因素。方法:基于2019年、2020年和2021年(截至6月)的现有病例记录进行回顾性研究。这项研究是在一个地区报告了白喉病例后进行的。这项研究是对公共卫生的回应,旨在为该地区提供具体的地理建议。数据来自报告的病例记录和免疫接种登记册。对数据进行定义变量分析。结果:在2019-2021年期间发现的366例病例中。2019年发生了近74%的病例,死亡率为7.7%。总共48%的病例发生在5-10岁年龄组,8月至12月期间病例数量不断增加,具有特定的地理分布。在所有病例中,164例(44.5%)从未接种过任何疫苗或不知道疫苗接种情况,87.9%的病例未接种第三剂百白破或五价疫苗,这与死亡率有统计学相关性。结论:未接种三剂百白破或五价疫苗的儿童白喉发病率较高。这表明免疫的重要作用,重点是所有剂量的疫苗,需要制定定制的宣传计划。
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发文量
17
审稿时长
12 weeks
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