Biological activities (antioxidant and antimicrobial activity) of the aqueous extracts and essential oil of Ammoides verticillata (Nounkha)

R. M. Said, N. Benmansour
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引用次数: 1

Abstract

The phytochemical review conducted on the aerial part Ammoides verticillata has revealed the presence of six chemical families: flavonoids, tannins; gallic tannins, anthocyanins and the coumarins, cateichic tannins. The aqueous extract of the Ammoides verticillata could bring back the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) to the yellow-colored diphenylpicrylhydrazine with an IC50 of 0.020 mg.mL-1. It is gifted with antioxidant activity, however it was less effective than vitamin C (0.001 mL-1). The essential oil of the Ammoides verticillata has presented a strong antimicrobial activity against Gram negatif germs targets of original clinical action: E. coli (ESBL) (37 mm), E. coli (39.5 mm), Klebsiella pneumoniae (36.5 mm) and especially with the yeast: Candida albicans ATCC 10231 (47 mm) and Saccharomyces cerevisie ATCC (42 mm), which are highly sensitive to the oil inhibitory action. However, the oil has presented a low activity against the bacteria P. aeruginosa (12.5 mm).
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毛茛(Ammoides verticillata, Nounkha)水提液和精油的生物活性(抗氧化和抗菌活性)
对轮叶Ammoides verticillata地上部分进行的植物化学审查揭示了六个化学家族的存在:类黄酮、单宁;没食子酸单宁,花青素和香豆素,儿茶酸单宁。轮叶Ammoides verticillata的水提取物可将稳定的2,2-二苯基-1-苦基肼(DPPH)还原为黄色二苯基丙肼,IC50为0.020mg.mL-1。它具有抗氧化活性,但效果不如维生素C(0.001 mL-1)。轮状Ammoides verticillata的精油对革兰氏阴性菌具有很强的抗菌活性,这些革兰氏阴性菌是最初临床作用的靶标:大肠杆菌(ESBL)(37mm)、大肠杆菌(39.5mm)、肺炎克雷伯菌(36.5mm),尤其是与酵母:白色念珠菌ATCC 10231(47mm)和酿酒酵母ATCC(42mm),它们对油的抑制作用高度敏感。然而,该油对铜绿假单胞菌的活性较低(12.5mm)。
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审稿时长
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