Treatment with Gaoziban Tablet Ameliorates Depression by Promoting GSK-3β Phosphorylation to Enhance the Wnt/β-catenin Activation in the Hippocampus of Rats
Xin Zou, Hailong Yin, Lei Shi, Hai-ping Li, Mengheng Wang, Wanci Song, Yang Luo, Wei-Liang Chen, Hezhen Wu, Yan-fang Yang, Junfeng Zan, Yan-wen Liu, Hanxiong Dan, Q. Yin, Pengtao You
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Abstract
Depression is a severe and recurrent mental disease and contributes to the global disease burden. However, there are limited effective treatments for depression. This study evaluated the effect of a compound Gaoziban tablet (CGZBT) on depression and explored its potential mechanisms that underlie its action in rats.
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