Pub Date : 2024-07-25DOI: 10.14218/jerp.2023.00008
Robert D. Friedberg, Megan Neelley, Joe Zucker, Andrea Hanna, Alexandra Mendelsohn, Alanna Greenberger, Noa Dunevich
{"title":"Cognitive-behavioral Therapy for Medical Non-adherence: A Topical Review and Clinical Recommendations","authors":"Robert D. Friedberg, Megan Neelley, Joe Zucker, Andrea Hanna, Alexandra Mendelsohn, Alanna Greenberger, Noa Dunevich","doi":"10.14218/jerp.2023.00008","DOIUrl":"https://doi.org/10.14218/jerp.2023.00008","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-19DOI: 10.14218/jerp.2023.00019
Ganesh Chandra Jagetia
{"title":"Bioactive Phytoconstituents and Medicinal Properties of Jamun (Syzygium cumini)","authors":"Ganesh Chandra Jagetia","doi":"10.14218/jerp.2023.00019","DOIUrl":"https://doi.org/10.14218/jerp.2023.00019","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-11DOI: 10.14218/jerp.2023.00026
Paul J. Fitzgerald
{"title":"Endogenous Opioids Contain Terminal Amino Acids that May Be Transformed to Catecholamines In Vivo and Modulate Pain","authors":"Paul J. Fitzgerald","doi":"10.14218/jerp.2023.00026","DOIUrl":"https://doi.org/10.14218/jerp.2023.00026","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141360316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-11DOI: 10.14218/jerp.2023.00025s
Temitope G. Olowe, M. Oyovwi, K. E. Nwangwa, E. P. Ohwin, Onome B Oghenetega
{"title":"Cytotoxic Properties of Cyclophosphamide: A Focus on Its Mechanistic Impacts on Male Gonadal Functions","authors":"Temitope G. Olowe, M. Oyovwi, K. E. Nwangwa, E. P. Ohwin, Onome B Oghenetega","doi":"10.14218/jerp.2023.00025s","DOIUrl":"https://doi.org/10.14218/jerp.2023.00025s","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140987554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-18DOI: 10.14218/jerp.2023.00007
Kasturee Hajra, Divya Tripathi, D. Maity
{"title":"Multicancer Early Detection Tests for Cancer Diagnosis","authors":"Kasturee Hajra, Divya Tripathi, D. Maity","doi":"10.14218/jerp.2023.00007","DOIUrl":"https://doi.org/10.14218/jerp.2023.00007","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139616025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.14218/jerp.2023.00018
Massimo Tusconi
{"title":"Neuronal Protective Effect of Nosustrophine in Cell Culture Models","authors":"Massimo Tusconi","doi":"10.14218/jerp.2023.00018","DOIUrl":"https://doi.org/10.14218/jerp.2023.00018","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139003037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and objectivesThe contamination of food by spoilage microorganisms is a major concern for public health. Food-borne pathogens are commonly encapsulated by biofilms. Bacteriocins of probiotic lactic acid bacteria, such as nisin and pediocin have been used as bio-preservatives to improve food safety and extend the storage period of some food types. Therefore, there is a need to explore the potential of bacteriocins to impede the growth and biofilm formation by food spoilage bacteria in milk.
{"title":"Plantaricin LD1 Inhibits the Growth and Biofilm Formation of <i>Staphylococcus aureus</i> in Milk","authors":"Manoj Kumar Yadav, Anshu Baldia, Santosh Kumar Tiwari","doi":"10.14218/jerp.2023.00011","DOIUrl":"https://doi.org/10.14218/jerp.2023.00011","url":null,"abstract":"Background and objectivesThe contamination of food by spoilage microorganisms is a major concern for public health. Food-borne pathogens are commonly encapsulated by biofilms. Bacteriocins of probiotic lactic acid bacteria, such as nisin and pediocin have been used as bio-preservatives to improve food safety and extend the storage period of some food types. Therefore, there is a need to explore the potential of bacteriocins to impede the growth and biofilm formation by food spoilage bacteria in milk.","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136059647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.14218/jerp.2023.00054
Simranjeet Kaur, Dilpreet Singh
Breast cancer can develop either in the tubes connecting the lobules of milk-producing glands to the nipple or the lobules themselves. GLOBOCAN 2021 reported an estimated 14.1 million new instances of cancer, 8.2 million cancer-related deaths, and 32.6 million people who had cancer for at least five years after their diagnosis. The development of genomic instability enables the acquisition of functional cells to become cancerous allowing the survival, proliferation, and dissemination of malignancy. These cells develop distinctive abilities as a result of acquired rare genetic mutations. Multistep tumor growth is caused by a succession of clonal expansions that are set off by the accidental discovery of an enabling mutant genotype. Hence, it is vital to identify defective genes in breast cancer and breast cancer therapy to mitigate the need for treatment. Critical analyses of various defective genes are compiled in this review.
{"title":"Genetic Contribution to Breast Cancer: A Critical Analysis of Penetrance Alleles as Susceptible Genes","authors":"Simranjeet Kaur, Dilpreet Singh","doi":"10.14218/jerp.2023.00054","DOIUrl":"https://doi.org/10.14218/jerp.2023.00054","url":null,"abstract":"Breast cancer can develop either in the tubes connecting the lobules of milk-producing glands to the nipple or the lobules themselves. GLOBOCAN 2021 reported an estimated 14.1 million new instances of cancer, 8.2 million cancer-related deaths, and 32.6 million people who had cancer for at least five years after their diagnosis. The development of genomic instability enables the acquisition of functional cells to become cancerous allowing the survival, proliferation, and dissemination of malignancy. These cells develop distinctive abilities as a result of acquired rare genetic mutations. Multistep tumor growth is caused by a succession of clonal expansions that are set off by the accidental discovery of an enabling mutant genotype. Hence, it is vital to identify defective genes in breast cancer and breast cancer therapy to mitigate the need for treatment. Critical analyses of various defective genes are compiled in this review.","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136059514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-04DOI: 10.14218/jerp.2023.00049
Joseph F. Murphy
{"title":"Therapeutic Vaccination and Cancer Immunotherapy","authors":"Joseph F. Murphy","doi":"10.14218/jerp.2023.00049","DOIUrl":"https://doi.org/10.14218/jerp.2023.00049","url":null,"abstract":"","PeriodicalId":73746,"journal":{"name":"Journal of exploratory research in pharmacology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46356211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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