REVIEW : PENGARUH PENAMBAHAN NANOSILVER TERHADAP AKTIVITAS ANTIOKSIDAN NANOPLATINA DALAM MEREDAM RADIKAL BEBAS

Abstract

Humans naturally experience a decline in bodily functions which results in the elimination of free radicals not working optimally. Oxidative stress caused by radicals can affect several degenerative diseases such as premature aging, cancer, and coronary heart disease. In an effort carried out research aimed to analyze and discuss the effect of nanosilver on the antioxidant activity of nanoplatines in reducing free radicals in various time variations, as well as to analyze and discuss the best concentration of nanosilver that supports the antioxidant activity of nanoplatines. The concentration used was 20 ppm nanoplatine and Nanosilver 5 to 25 ppm. According to previous research, to study the antioxidant activity using a UV-Vis spectrophotometer as a tool to characterize platinum nanoparticles and DPPH methods to discuss the activity of reducing free radicals because they require antioxidants. Results showed that the addition of nanosilver with concentrations of 5, 10, 15, 20 and 25 ppm had a significant influence on the antioxidant activity of nanoplatines. The results of the average reduction in combined nanosilver 20 ppm with variations in the concentration of nanoplatines 5, 10, 15, 20, and 25 ppm were 75.90%; 82.90%; 86.61%; 87.95%; and 85.19%. The effect of the addition of nanoplatinum on the antioxidant activity of nanosilver has a synergy due to an increase in the yield of percent reduction from each increase in concentration with the optimum results on the addition of 20 ppm nanoplatina with a yield of 87.95% [Hesti, Nita. (2017)].   Keywords : Nanosilver, Nanoplatina, Antioxidant activity, DPPH