Biodegradable Polymer Films with a Natural Antibacterial Extract as Novel Periodontal Barrier Membranes

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS International Journal of Biomaterials Pub Date : 2019-08-14 DOI:10.1155/2019/7932470
Z. B. Ahi, Nergis Zeynep Renkler, Mine Gul Seker, K. Tuzlakoglu
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引用次数: 18

Abstract

Biodegradable composite membranes containing propolis were produced from PCL/PLLA blends using a simple and low-cost solvent casting method, and subsequently their physicochemical, mechanical, and antibacterial properties were characterized. SEM analysis revealed that the addition of propolis has created honeycomb-like structures on the film surfaces. The flexibility of the films increased in the presence of propolis, which may provide ease of use during application. Propolis disrupted the organized structure of both polymers at the molecular level and caused decreases in the melting points. The films with propolis showed faster degradation in physiological conditions due to this molecular disruption. Moreover, the PLLA/PCL/propolis composite films exhibited remarkable antibacterial activities against S. aureus. Collectively, the data suggest that the produced films might be used as an alternative to exiting barrier membranes in guided tissue regeneration.
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含天然抗菌提取物的生物可降解聚合物膜作为新型牙周屏障膜
采用简单、低成本的溶剂浇铸法,由PCL/PLLA共混物制备了含有蜂胶的可生物降解复合膜,并对其理化、力学和抗菌性能进行了表征。SEM分析表明,蜂胶的加入在薄膜表面形成了蜂窝状结构。在蜂胶存在的情况下,薄膜的柔韧性增加,这可以在应用过程中提供易用性。蜂胶在分子水平上破坏了两种聚合物的组织结构,导致熔点降低。由于这种分子破坏,含有蜂胶的薄膜在生理条件下表现出更快的降解。此外,PLLA/PCL/蜂胶复合膜对金黄色葡萄球菌具有显著的抗菌活性。总的来说,数据表明,在引导组织再生中,所制备的薄膜可以作为退出屏障膜的替代品。
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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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