Anaphylaxis to food additives

Q3 Medicine Allergo Journal International Pub Date : 2022-03-11 DOI:10.1007/s40629-022-00203-y

Regina Treudler, Jan Christoph Simon

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引用次数: 4

Abstract

A variety of additives found in foodstuffs have been associated with triggering of a number of clinical pictures. Hypersensitivity reactions of allergic and non-allergic etiology have been widely described, but are reported to be rare overall. This review presents a selection of food additives for which anaphylactic reactions have been described. These include colorants (e.g., tartrazine, carmine, patent blue), preservatives (e.g., sulfites, sodium benzoate), and thickeners/gelling agents (e.g., carboxymethylcellulose, guar, gum arabic). Possible diagnostic procedures (skin test, specific IgE, cellular antigen stimulation test, oral provocation) are presented. For those affected, avoidance of consumption is facilitated by the mandatory declaration (class name, E‑number/designation) required in the European Union. Only sulfur dioxide and sulfites have to be highlighted as food allergens, depending on the concentration. Due to the limited diagnostic procedures available, it cannot be excluded that the frequency of hypersensitivity to food additives is underestimated.

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对食品添加剂过敏

在食品中发现的各种添加剂与许多临床图片的触发有关。过敏性和非过敏性病因的超敏反应已被广泛描述，但据报道总体上很罕见。这篇综述介绍了过敏反应已被描述的食品添加剂的选择。其中包括着色剂（如柠檬黄、胭脂红、专利蓝）、防腐剂（如亚硫酸盐、苯甲酸钠）和增稠剂/胶凝剂（如羧甲基纤维素、瓜尔胶、阿拉伯树胶）。介绍了可能的诊断程序（皮肤试验、特异性IgE、细胞抗原刺激试验、口服激发）。对于那些受影响的人来说，欧盟要求的强制性声明（类名、E号/名称）有助于避免消费。根据浓度的不同，只有二氧化硫和亚硫酸盐必须被强调为食物过敏原。由于可用的诊断程序有限，不能排除低估了对食品添加剂超敏反应的频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Allergo Journal International Medicine-Immunology and Allergy

CiteScore

4.60

自引率

0.00%

发文量

期刊介绍： Allergo Journal International is the official Journal of the German Society for Applied Allergology (AeDA) and the Austrian Society for Allergology and Immunology (ÖGAI). The journal is a forum for the communication and exchange of ideas concerning the various aspects of allergy (including related fields such as clinical immunology and environmental medicine) and promotes German allergy research in an international context. The aim of Allergo Journal International is to provide state of the art information for all medical and scientific disciplines that deal with allergic, immunological and environmental diseases. Allergo Journal International publishes original articles, reviews, short communications, case reports, and letters to the editor. The articles cover topics such as allergic, immunological and environmental diseases, the latest developments in diagnosis and therapy as well as current research work concerning antigens and allergens and aspects related to occupational and environmental medicine. In addition, it publishes clinical guidelines and position papers approved by expert panels of the German, Austrian and Swiss Allergy Societies. All submissions are reviewed in single-blind fashion by at least two reviewers. Originally, the journal started as a German journal called Allergo Journal back in 1992. Throughout the years, English articles amounted to a considerable portion in Allergo Journal. This was one of the reasons to extract the scientific content and publish it in a separate journal. Hence, Allergo Journal International was born and now is the international continuation of the original German journal. Nowadays, all original content is published in Allergo Journal International first. Later, selected manuscripts will be translated and published in German and included in Allergo Journal.