{"title":"Pegfilgrastim-related thoracic aortitis: A case report and literature review","authors":"Chikako Sekine , Sasagu Kurozumi , Hirotoshi Kawashima , Koichi Hirose , Jun Horiguchi","doi":"10.1016/j.cpccr.2023.100250","DOIUrl":null,"url":null,"abstract":"<div><p>Pegfilgrastim can prevent febrile neutropenia during chemotherapy and helps maintain treatment intensity. Aortitis is a rare and serious adverse event associated with pegfilgrastim therapy. The mechanism of pegfilgrastim-related aortitis is unknown. We report a case of pegfilgrastim-related thoracic aortitis during breast cancer chemotherapy in a 69-year-old woman. This case report and literature review draws attention towards this rare adverse event with increasing incidence in recent years.</p></div>","PeriodicalId":72741,"journal":{"name":"Current problems in cancer. Case reports","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current problems in cancer. Case reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666621923000340","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Pegfilgrastim can prevent febrile neutropenia during chemotherapy and helps maintain treatment intensity. Aortitis is a rare and serious adverse event associated with pegfilgrastim therapy. The mechanism of pegfilgrastim-related aortitis is unknown. We report a case of pegfilgrastim-related thoracic aortitis during breast cancer chemotherapy in a 69-year-old woman. This case report and literature review draws attention towards this rare adverse event with increasing incidence in recent years.
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