Predictive significance of a complex approach in determining the vascular wall stiffness parameters in patients with arterial hypertension and in patients with arterial hypertension after ischemic stroke

Abstract

The article presents the information about the predictive significance of a complex approach in determining vascular wall stiffness parameters. A total of 159 people with arterial hypertension (AH) and AH after a previous ischemic stroke were examined. A model with a conditional linear predictor (LP) was constructed, using a binary regression equation with a probit-link function for prediction of cardiovascular events. LP is a combination of indicators such as age (А), glomerular filtration rate (CKD-EPI), pulse wave velocity (PWV), intima- media thickness (IMT), cardio-ankle vascular index (CAVI) and augmentation index (AI). The equation has the following form: LP = –6.6139 – 0.0978A + 0.031CKDEPI + 0.0758PWV + 3.2086IMT + 0.4421CAVI + 1.2429AI. The cut-off threshold for LP = 0.0238, sensitivity (Se) 85.71 %, specificity (Sp) 77 % and accuracy (Acc) 78.07 %.