Research progress in colorectal cancer screening

Jing-peng Hao, Hui Wang, Ganggang Shi, Mei Han, Penghao Li
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Abstract

The incidence of colorectal cancer is high threatening human health. About 60%~70% cases of CRC are derived from colorectal polyps, which can be treated by endoscopic electrotomy to prevent the possibility of canceration. Therefore, in the prevention and treatment of CRC, the role of screening is of great significance. CRC screening methods include the most commonly used fecal occult blood test (FOBT) and the more sensitive fecal immunochemical test (FIT), cost-effective fiber sigmoidoscopy and colonoscopy, CT colonoscopy (CTC), and fecal DNA testing and immature CRC hematology screening. In this paper, the CRC screening technologies were reviewed, including the principles, characteristics and the latest research progress to provide a theoretical basis for the application and development of CRC screening technology. Key words: Colorectal cancer; Screening technology; Colonoscopy
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结直肠癌筛查研究进展
结直肠癌是危害人类健康的高发疾病。约60%~70%的结直肠癌源于结直肠息肉,可采用内镜下电切术治疗,防止癌变的可能性。因此,在预防和治疗结直肠癌中,筛查的作用具有重要意义。CRC筛查方法包括最常用的粪便隐血试验(FOBT)和更敏感的粪便免疫化学试验(FIT),成本效益高的乙状结肠纤维镜和结肠镜检查,CT结肠镜检查(CTC),以及粪便DNA检测和未成熟CRC血液学筛查。本文对结直肠癌筛查技术的原理、特点及最新研究进展进行综述,为结直肠癌筛查技术的应用和发展提供理论依据。关键词:结直肠癌;筛选技术;结肠镜检查
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