ChoKs as a Promising Therapeutic Target for a Variety of Pathologies

S. Ibrahim
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Abstract

Alterations in cell metabolism represent a common cause of human diseases. Changes in lipid profiles are not an exception to this rule, including those lipids that are produced via the choline kinase (ChoK) pathway. ChoK catalyzes the conversion of choline to phosphocholine via the transfer of a phosphate group from ATP to choline.
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ChoKs有望成为多种病理学的治疗靶点
细胞代谢的改变是人类疾病的常见原因。脂质分布的变化也不例外,包括通过胆碱激酶(ChoK)途径产生的脂质。ChoK通过磷酸基团从ATP转移到胆碱来催化胆碱转化为磷酸胆碱。
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