{"title":"Effects of renal Na-Cl co-transporter on calcium homeostasis and bone metabolism","authors":"Bingbin Zhao, Lei Zhang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.04.009","DOIUrl":null,"url":null,"abstract":"Osteoporosis is a global public health problem. The kidney, especially the Na-Cl co-transporter (NCC) located in the renal distal tubular cells, which is an important transporter for urinary calcium regulation, plays an important role in calcium homeostasis and bone metabolism. This review summarized recent researches on effects and mechanisms of NCC on calcium and bone metabolism. \n \n \nKey words: \nNa-Cl co-transporter; Calcium homeostasis; Bone metabolism","PeriodicalId":9877,"journal":{"name":"中华临床营养杂志","volume":"27 1","pages":"251-256"},"PeriodicalIF":0.0000,"publicationDate":"2019-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华临床营养杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.04.009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0
Abstract
Osteoporosis is a global public health problem. The kidney, especially the Na-Cl co-transporter (NCC) located in the renal distal tubular cells, which is an important transporter for urinary calcium regulation, plays an important role in calcium homeostasis and bone metabolism. This review summarized recent researches on effects and mechanisms of NCC on calcium and bone metabolism.
Key words:
Na-Cl co-transporter; Calcium homeostasis; Bone metabolism
期刊介绍:
The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch.
The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.