Maintained Renal Function by Blood Pressure Control in Patient with Diabetic Kidney Disease (DKD)

H. Bando, Noboru Iwatsuki, M. Okada, T. Ogawa, K. Sakamoto
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Abstract

The case involves a 74-year-old male with type 2 diabetes (T2D), hypertension, dyslipidemia, and diabetic kidney disease (DKD) at nephropathy stage G3b. He has been receiving treatment with insulin and anti-hypertensive agents (AHAs). In July 2021, his HbA1c was elevated to 7.9%. As a result, the extent of his low carbohydrate diet (LCD) was increased, and insulin doses were raised. The AHAs were changed from Olmesartan to Valsartan/Amlodipine, and Irbesartan/Amlodipine until 2023. By January 2023, his HbA1c had decreased to 6.8%, and his eGFR (CKD-EPI) had remained stable at 34-48 mL/min/1.73/m2 for 4 years. A recent study demonstrated clinical improvement in renal function through continuous LCD in patients with DKD.
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通过控制血压维持糖尿病肾病患者的肾功能
该病例涉及一名74岁男性,患有2型糖尿病(T2D)、高血压、血脂异常和肾病G3b期糖尿病肾病(DKD)。他一直在接受胰岛素和抗高血压药物(AHA)的治疗。2021年7月,他的HbA1c升高至7.9%。因此,他的低碳水化合物饮食(LCD)范围增加,胰岛素剂量增加。AHA从奥美沙坦改为缬沙坦/氨氯地平,并在2023年前改为厄贝沙坦/氨氯地平。到2023年1月,他的HbA1c已降至6.8%,他的eGFR(CKD-EPI)在4年内稳定在34-48 mL/min/1.73/m2。最近的一项研究表明,DKD患者通过连续液晶显示可改善肾功能。
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