Comparison of recovery time with target controlled infusion of propofol with sevoflurane anesthesia using bispectral index monitoring in vitrectomy surgery

IF 0.2 Q4 ANESTHESIOLOGY Anaesthesia, Pain & Intensive Care Pub Date : 2021-12-01 DOI:10.35975/apic.v25i6.1689
A. Tantri, R. B. Sukmono, Linda Stefanie Atmadja
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Abstract

Background: Rapid recovery after anesthesia is critical and is associated with the anesthetic agents used. The bispectral index (BIS) monitoring to guide anesthetic agents' doses may play a significant role in the recovery time. This study compared recovery time after Target Controlled Infusion (TCI) of propofol with sevoflurane anesthesia by using BIS monitoring during vitrectomy surgery.  Methodology: This was a prospective observational, randomized study on 40 patients aged 18–65 y, physical status ASA I–II, body mass index (BMI) 18–30 kg/m2, who underwent vitrectomy surgery. Subjects were randomly assigned into two groups, Group P – the TCI propofol group, and Group S – the sevoflurane group. Subjects in the Group P received TCI propofol (Schnider), and subjects in the Group S received sevoflurane for anesthesia maintenance, with a targeted BIS score of 40–60. Inj. fentanyl 1 µg/kg was administered if there was an increase in blood pressure, heart rate and/or BIS that could not be overcome by increasing the dose of TCI propofol or sevoflurane. Recovery time was calculated from when the maintenance regimen was stopped until the patient was able to obey simple commands. Recovery time, fentanyl consumption, postoperative agitation, nausea and vomiting incidence were noted and analyzed with SPSS v21.0 for Windows. T–Test or Mann–Whitney U test was performed to analyze the data.  Result: Recovery time in the Group P [11.5 (5–25) min)] was not significantly different from the Group S [9 (4–18) min, p = 0.139]. Total fentanyl consumption was higher in the Group P than in the Group S (1.765 vs. 1.428 µg/kg). The frequency of agitation during recovery was higher in the Group S than in the Group P (30% vs. 20%) Conclusion: There was no significant difference in recovery time between target controlled infusion of propofol and BIS controlled sevoflurane anesthesia in vitrectomy. Total fentanyl consumption was higher in the Group P than in the sevoflurane group. The impact of these anesthetic regimens on postoperative agitation needs further investigation. Key words: Intravenous anesthesia; Bispectral index monitoring; BIS;  Propofol; Sevoflurane; Target Controlled Infusion; TCI; Vitrectomy Citation: Tantri AR, Sukmono RB, Atmadja LS. Comparison of recovery time with target controlled infusion of propofol with sevoflurane anesthesia using bispectral index monitoring in vitrectomy surgery. Anaesth. pain intensive care 2021;25(6):707–712: DOI: 10.35975/apic.v25i6.1689
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应用双频谱指数监测靶控输注丙泊酚与七氟醚麻醉在玻璃体切除术中恢复时间的比较
背景:麻醉后的快速恢复是至关重要的,并且与所使用的麻醉剂有关。双频谱指数(BIS)监测可以指导麻醉剂的剂量,这可能在恢复时间中发挥重要作用。本研究通过BIS监测比较了玻璃体切除术中靶向控制输注丙泊酚和七氟醚麻醉后的恢复时间。方法:这是一项前瞻性观察性随机研究,对象为40名年龄在18-65岁、身体状况ASA I-II、体重指数(BMI)为18-30 kg/m2的接受玻璃体切除手术的患者。受试者被随机分为两组,P组为TCI丙泊酚组,S组为七氟醚组。P组受试者接受TCI丙泊酚(Schnider),S组受试对象接受七氟醚维持麻醉,目标BIS评分为40-60。Inj。如果血压、心率和/或BIS的增加无法通过增加TCI丙泊酚或七氟醚的剂量来克服,则给予芬太尼1µg/kg。恢复时间从停止维持方案开始计算,直到患者能够服从简单的命令。记录恢复时间、芬太尼用量、术后躁动、恶心呕吐发生率,并用SPSS v21.0 for Windows进行分析。进行T检验或Mann-Whitney U检验来分析数据。结果:P组的恢复时间[11.5(5-25)分钟]与S组[9(4-18)分钟,P=0.139]没有显著差异。P组的芬太尼总消耗量高于S组(1.765 vs.1.428µg/kg)。S组在恢复过程中的搅动频率高于P组(30%对20%)。结论:在玻璃体切除术中,靶控输注丙泊酚和BIS控制七氟醚麻醉在恢复时间上没有显著差异。P组芬太尼总消耗量高于七氟醚组。这些麻醉方案对术后躁动的影响需要进一步研究。关键词:静脉麻醉;双谱指数监测;BIS;异丙酚;七氟醚;靶向控制输液;TCI;玻璃体切除术引文:Tantri AR,Sukmono RB,Atmadja LS。在玻璃体切除术中使用双频谱指数监测与靶控输注丙泊酚和七氟醚麻醉的恢复时间比较。Anaesth。疼痛重症监护2021;25(6):707–712:DOI:10.35975/apic.v25i6.1689
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CiteScore
0.40
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0.00%
发文量
56
审稿时长
4 weeks
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