Frontalis Suspension Surgery for Patients with Essential Blepharospasm Unresponsive to Botulinum Toxin Injections

Sujin Yeo, K. Woo, Yoon-Duck Kim
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Abstract

Purpose: To report the efficacy of frontalis suspension using a silicone rod or preserved fascia lata for patients with blepharospasm who exhibit persistent symptoms and visual dysfunction unresponsive to botulinum injections.Methods: The clinical records of five patients (10 eyes) with essential blepharospasm who underwent frontalis suspension were reviewed. Patients who continued to report eyelid-opening difficulties despite prior administration of botulinum toxin were included.Results: The mean patient age was 60.2 years; and 40% of the patients were women. The frontalis was suspended using silicone rods (n = 3) or preserved fascia lata (n = 2). Blepharospasm frequency and severity were measured using the Jankovic Rating Scale (JRS). Compared with preoperative scores, the summed JRS scores decreased 1 week, 1 month, and 3 months after surgery. Postoperatively, two patients (40%) did not require further botulinum toxin injections. In three patients, the intervals between injections were increased after surgery. No patient experienced any significant complication.Conclusions: Frontalis suspension is safe and effective for patients with blepharospasm and apraxia of eyelid opening, who have not responded to botulinum toxin injections.
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对肉毒杆菌毒素注射无反应的原发性眼睑痉挛患者的额叶悬吊术
目的:报告使用硅胶棒或保留阔筋膜的额肌悬液治疗对肉毒杆菌注射无反应的持续症状和视觉功能障碍的眼睑痉挛患者的疗效。方法:对5例(10眼)原发性眼睑痉挛患者行额肌悬吊术的临床资料进行回顾性分析。尽管之前服用肉毒杆菌毒素,但仍报告眼睑张开困难的患者也包括在内。结果:患者平均年龄60.2岁;女性占40%。使用硅胶棒(n=3)或保留的阔筋膜(n=2)悬吊额肌。使用Jankovic评分量表(JRS)测量眼睑痉挛的频率和严重程度。与术前评分相比,术后1周、1个月和3个月的JRS总分均有所下降。术后,两名患者(40%)不需要进一步注射肉毒杆菌毒素。在三名患者中,术后注射间隔时间增加。没有患者出现任何严重并发症。结论:额悬吊术治疗对肉毒杆菌毒素注射无反应的眼睑痉挛和眼睑开放失用症是安全有效的。
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