N. Fatmawati, Novi Anggreini, R. Saputri, Tjitjik Srie Tjahjandarie, M. Tanjung
{"title":"AKTIVITAS ANTIMALARIA SENYAWA FLAVANON TERISOPRENILASI DARI KULIT BATANG Erythrina fusca L.","authors":"N. Fatmawati, Novi Anggreini, R. Saputri, Tjitjik Srie Tjahjandarie, M. Tanjung","doi":"10.30872/JKM.V16I1.586","DOIUrl":null,"url":null,"abstract":"Two isoprenylated flavanones namely as lonchocarpol A (1) dan lupinifolin (2) were isolated from the stem bark of Limonia accidissima L. Erythrina fusca L. Their structures were determined based on spectroscopic data such as UV, IR, MS and NMR. Compounds 1–2 were evaluated for their antimalarial against Plasmodium falciparum strain 3D7 showing their IC50 were 1.18 and 0.8 µg/ml, respectively and very high activity. \n ","PeriodicalId":31725,"journal":{"name":"Jurnal Kimia Mulawarman","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Kimia Mulawarman","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30872/JKM.V16I1.586","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Two isoprenylated flavanones namely as lonchocarpol A (1) dan lupinifolin (2) were isolated from the stem bark of Limonia accidissima L. Erythrina fusca L. Their structures were determined based on spectroscopic data such as UV, IR, MS and NMR. Compounds 1–2 were evaluated for their antimalarial against Plasmodium falciparum strain 3D7 showing their IC50 were 1.18 and 0.8 µg/ml, respectively and very high activity.
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