{"title":"The latest research progress of metformin on the effect beyond hypoglycemic","authors":"Lili Deng, Xiaotong Zhao","doi":"10.3760/CMA.J.ISSN.1008-6315.2019.06.021","DOIUrl":null,"url":null,"abstract":"Objective \nMetformin (MET) is the first-line medications of choice for patients with type 2 diabetes.In recent years, a large number of studies at home and abroad have shown that metformin not only has significant effects in controlling blood sugar level of diabetic patients and intervening in impaired glucose tolerance, but also has \" magical\" effects in in the field of hypoglycemic outside.In addition to the early discovery that metformin can be used to treat metabolic syndrome and polycystic ovary syndrome, control body weight, blood pressure, blood lipid, and reduce the risk of cardiovascular events, metformin can also play anti-tumor, anti-inflammatory effects, delay aging, and treat mental disorders such as depression.This article reviews the effect of metformin in the field out of hypoglycemic. \n \n \nKey words: \nMetformin; Neuropsychiatric disorders; Intestinal flora; Osteogenesis; Anti-inflammatory and anti-aging","PeriodicalId":10365,"journal":{"name":"中国综合临床","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国综合临床","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1008-6315.2019.06.021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
Metformin (MET) is the first-line medications of choice for patients with type 2 diabetes.In recent years, a large number of studies at home and abroad have shown that metformin not only has significant effects in controlling blood sugar level of diabetic patients and intervening in impaired glucose tolerance, but also has " magical" effects in in the field of hypoglycemic outside.In addition to the early discovery that metformin can be used to treat metabolic syndrome and polycystic ovary syndrome, control body weight, blood pressure, blood lipid, and reduce the risk of cardiovascular events, metformin can also play anti-tumor, anti-inflammatory effects, delay aging, and treat mental disorders such as depression.This article reviews the effect of metformin in the field out of hypoglycemic.
Key words:
Metformin; Neuropsychiatric disorders; Intestinal flora; Osteogenesis; Anti-inflammatory and anti-aging
期刊介绍：
Clinical Medicine of China is an academic journal organized by the Chinese Medical Association (CMA), which mainly publishes original research papers, reviews and commentaries in the field.
Clinical Medicine of China is a source journal of Peking University (2000 and 2004 editions), a core journal of Chinese science and technology, an academic journal of RCCSE China Core (Extended Edition), and has been published in Chemical Abstracts of the United States (CA), Abstracts Journal of Russia (AJ), Chinese Core Journals (Selection) Database, Chinese Science and Technology Materials Directory, Wanfang Database, China Academic Journal Database, JST Japan Science and Technology Agency Database (Japanese) (2018) and other databases.
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