Indirect Sinus Augmentation With and Without the Addition of a Biomaterial: A Randomized Controlled Clinical Trial.

Abstract

PURPOSE The aim of this study was to compare the results of indirect sinus augmentation with and without the addition of a biomaterial. MATERIALS AND METHODS Thirty patients aged 40 to 60 years participated in this randomized controlled clinical trial. After closed sinus lift operation, patients were randomly and equally divided into blood clot control and acemannan sponge graft groups. Simultaneous implant placement was then performed. Cone beam computed tomography was performed immediately and at 3 and 6 months postoperation. Bone formation was evaluated by the radiographic endo-sinus bone gain percentage around the implant. RESULTS Compared with the control group, the acemannan-treated group had a significantly greater radiographic endo-sinus bone gain percentage of approximately 2.4- and 2-fold at 3 and 6 months postsurgery, respectively (P < 0.05). CONCLUSION The addition of a biomaterial (Acemannan) with indirect sinus augmentation and simultaneous implant placement significantly enhances bone formation at 3 and 6 months postsurgery.