Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000919
Andrea Ravidà, I-Ching Wang, Gilberto Sammartino, Shayan Barootchi, Mustafa Tattan, Giuseppe Troiano, Luigi Laino, Gaetano Marenzi, Ugo Covani, Hom-Lay Wang
Purpose: To compare the clinical and patient-reported outcomes of ≤6-mm implants with those of ≥10-mm implants placed after both lateral and transcrestal sinus floor elevation.
Materials and methods: Using PubMed (MEDLINE), EMBASE, and Cochrane, a literature search for randomized controlled trials was performed. All the outcome variables were evaluated through a quantitative meta-analysis, and the influence of other clinical covariates were determined with a metaregression. For the survival outcomes, trial sequential analysis (TSA) was performed to adjust results for type I and II errors and to analyze the power of the available evidence.
Results: After full-text reading, 12 studies were included in the analyses. No statistically significant difference was found after 3 years between the 2 study groups (P = 0.36). Short implants displayed fewer biological complications (P = 0.05), less marginal bone loss (MBL) from implant placement (P < 0.01), and reduced surgical time and treatment cost. However, long implants showed a statistically significant smaller number of prosthetic complications (P = 0.03). TSA confirmed the results of the meta-analysis, revealing that additional studies are needed due to low statistical power of the available evidence.
Conclusion: The placement of short implants is a predictable option in treating patients with maxillary atrophy up to a 3-year follow-up. Studies with a longer observational period are needed to study the long-term performance of these implants.
{"title":"Prosthetic Rehabilitation of the Posterior Atrophic Maxilla, Short (≤6 mm) or Long (≥10 mm) Dental Implants? A Systematic Review, Meta-analysis, and Trial Sequential Analysis: Naples Consensus Report Working Group A.","authors":"Andrea Ravidà, I-Ching Wang, Gilberto Sammartino, Shayan Barootchi, Mustafa Tattan, Giuseppe Troiano, Luigi Laino, Gaetano Marenzi, Ugo Covani, Hom-Lay Wang","doi":"10.1097/ID.0000000000000919","DOIUrl":"https://doi.org/10.1097/ID.0000000000000919","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the clinical and patient-reported outcomes of ≤6-mm implants with those of ≥10-mm implants placed after both lateral and transcrestal sinus floor elevation.</p><p><strong>Materials and methods: </strong>Using PubMed (MEDLINE), EMBASE, and Cochrane, a literature search for randomized controlled trials was performed. All the outcome variables were evaluated through a quantitative meta-analysis, and the influence of other clinical covariates were determined with a metaregression. For the survival outcomes, trial sequential analysis (TSA) was performed to adjust results for type I and II errors and to analyze the power of the available evidence.</p><p><strong>Results: </strong>After full-text reading, 12 studies were included in the analyses. No statistically significant difference was found after 3 years between the 2 study groups (P = 0.36). Short implants displayed fewer biological complications (P = 0.05), less marginal bone loss (MBL) from implant placement (P < 0.01), and reduced surgical time and treatment cost. However, long implants showed a statistically significant smaller number of prosthetic complications (P = 0.03). TSA confirmed the results of the meta-analysis, revealing that additional studies are needed due to low statistical power of the available evidence.</p><p><strong>Conclusion: </strong>The placement of short implants is a predictable option in treating patients with maxillary atrophy up to a 3-year follow-up. Studies with a longer observational period are needed to study the long-term performance of these implants.</p>","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000919","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37395289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000935
E. Anitua, M. Alkhraisat
PURPOSE Short implants are a minimally invasive alternative in the management of alveolar bone atrophy. This study aimed to assess the influence of the surgical approach (1-stage vs 2-stage) on the 15-year survival and marginal bone loss of short implants in a fixed complete denture. MATERIALS AND METHODS A retrospective clinical study was conducted in a single private dental clinic that included short implants placed between January 2001 and December 2002. RESULTS Forty-one short implants supported 18 screw-retained complete dentures. The mean follow-up time was 15 ± 3 years. The surgical approach (1-stage vs 2-stage) did not significantly affect implant survival and marginal bone loss. The implant survival rate was 90.2%. CONCLUSIONS Short dental implants could be predictably indicated to support fixed complete dentures. The implants could be placed through a 1- or 2-stage surgery.
{"title":"Fifteen-Year Follow-up of Short Dental Implants in the Completely Edentulous Jaw: Submerged Versus Nonsubmerged Healing.","authors":"E. Anitua, M. Alkhraisat","doi":"10.1097/ID.0000000000000935","DOIUrl":"https://doi.org/10.1097/ID.0000000000000935","url":null,"abstract":"PURPOSE\u0000Short implants are a minimally invasive alternative in the management of alveolar bone atrophy. This study aimed to assess the influence of the surgical approach (1-stage vs 2-stage) on the 15-year survival and marginal bone loss of short implants in a fixed complete denture.\u0000\u0000\u0000MATERIALS AND METHODS\u0000A retrospective clinical study was conducted in a single private dental clinic that included short implants placed between January 2001 and December 2002.\u0000\u0000\u0000RESULTS\u0000Forty-one short implants supported 18 screw-retained complete dentures. The mean follow-up time was 15 ± 3 years. The surgical approach (1-stage vs 2-stage) did not significantly affect implant survival and marginal bone loss. The implant survival rate was 90.2%.\u0000\u0000\u0000CONCLUSIONS\u0000Short dental implants could be predictably indicated to support fixed complete dentures. The implants could be placed through a 1- or 2-stage surgery.","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61733197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000925
Abhishek Patel, Henry Greenwell, Margaret Hill, Brian Shumway, Aaron Radmall
Purpose: The primary aim of this randomized, controlled, blinded, clinical trial was to compare a mix of particulate allograft and harvested autogenous particles (Autogenous) to an osteoinductive demineralized bone matrix (DBM) allograft on clinical and histologic outcomes for horizontal ridge augmentation procedure.
Materials and methods: Fourteen patients with a horizontal ridge defect with at least 1 adjacent tooth were entered into this study. The test group of 7 subjects received corticocancellous particulate allograft (Mineross) mixed with autogenous bone chips (70:30) harvested using a bone scraper (SafeScraper TWIST). Seven subjects in the control group received DBM (Optecure-CCC). Both groups had a corticocancellous particulate allograft overlay and an acellular dermis membrane (ADMG) (AlloDerm GBR) to cover the grafts.
Results: For the Autogenous group, there was a gain of 3.5 ± 1.4 mm while the DBM group gained 3.8 ± 1.6 mm (P < 0.05). Vertical change was minimal for both groups (P > 0.05). The Autogenous group had a mean of 35% vital bone while the DBM had 39% (P > 0.05).
Conclusions: Both treatments provided similar gain of ridge width and minimal loss of ridge height. The autogenous bone chips did not provide any additional benefit when compared with allograft alone that had lot verified osteoinductive activity.
目的:这项随机、对照、盲法临床试验的主要目的是比较颗粒同种异体移植物和收获的自体颗粒(自体)与骨诱导脱矿骨基质(DBM)同种异体移植物在水平嵴增强手术中的临床和组织学结果。材料与方法:选取14例水平牙脊缺损伴至少1颗邻牙的患者为研究对象。试验组7名受试者接受皮质松质颗粒同种异体移植物(Mineross)与自体骨片(70:30)混合，使用骨刮板(SafeScraper TWIST)采集。对照组7例接受DBM (Optecure-CCC)治疗。两组均有皮质松质颗粒异体移植物覆盖层和脱细胞真皮膜(ADMG) (AlloDerm GBR)覆盖移植物。结果:自体组增厚3.5±1.4 mm, DBM组增厚3.8±1.6 mm (P < 0.05)。两组的垂直变化最小(P > 0.05)。自体组平均存活骨35%，DBM组平均存活骨39% (P > 0.05)。结论:两种治疗方法均可获得相似的脊宽增益和最小的脊高损失。与同种异体骨片相比，自体骨片没有提供任何额外的益处，而同种异体骨片具有许多已证实的骨诱导活性。
{"title":"Ridge Augmentation Comparing an Allograft Plus Autogenous Bone Chips to an Osteoinductive Demineralized Bone Matrix: A Clinical and Histologic Study in Humans.","authors":"Abhishek Patel, Henry Greenwell, Margaret Hill, Brian Shumway, Aaron Radmall","doi":"10.1097/ID.0000000000000925","DOIUrl":"https://doi.org/10.1097/ID.0000000000000925","url":null,"abstract":"<p><strong>Purpose: </strong>The primary aim of this randomized, controlled, blinded, clinical trial was to compare a mix of particulate allograft and harvested autogenous particles (Autogenous) to an osteoinductive demineralized bone matrix (DBM) allograft on clinical and histologic outcomes for horizontal ridge augmentation procedure.</p><p><strong>Materials and methods: </strong>Fourteen patients with a horizontal ridge defect with at least 1 adjacent tooth were entered into this study. The test group of 7 subjects received corticocancellous particulate allograft (Mineross) mixed with autogenous bone chips (70:30) harvested using a bone scraper (SafeScraper TWIST). Seven subjects in the control group received DBM (Optecure-CCC). Both groups had a corticocancellous particulate allograft overlay and an acellular dermis membrane (ADMG) (AlloDerm GBR) to cover the grafts.</p><p><strong>Results: </strong>For the Autogenous group, there was a gain of 3.5 ± 1.4 mm while the DBM group gained 3.8 ± 1.6 mm (P < 0.05). Vertical change was minimal for both groups (P > 0.05). The Autogenous group had a mean of 35% vital bone while the DBM had 39% (P > 0.05).</p><p><strong>Conclusions: </strong>Both treatments provided similar gain of ridge width and minimal loss of ridge height. The autogenous bone chips did not provide any additional benefit when compared with allograft alone that had lot verified osteoinductive activity.</p>","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000925","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37372999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000915
Suya Chen, Qianmin Ou, Xuefeng Lin, Yan Wang
Background: During implantation planning, dentists should be able to make an informed decision regarding whether to use an implant template to assist the surgery.
Purpose: The aim of this meta-analysis was to assess the results of implantation with or without an implant template based on the accuracy, survival rate, and other considerations.
Materials and methods: In January 2018, a systematic review was undertaken for randomized controlled trials and retrospective and prospective cohort studies with relevance to implant accuracy and the survival rate between the implant template and free-hand method. The odds ratios (ORs) of the survival rate and the mean difference of accuracy deviation from the selected papers were estimated by meta-analysis.
Results: Of the 362 screened articles, 6 studies were included in the meta-analysis. Comparison of the survival rate of implant surgery with or without an implant template revealed no significant result (OR = 1.71, 95% confidence interval [CI] 0.65-4.51). Significant differences in accuracy were observed in angular (mean difference = -5.45 degrees, 95% CI -0.66 to -4.24 degrees) and apical deviation (mean difference = -0.83 mm, 95% CI -1.12 to -0.54).
Conclusions: With the technology of computer-aided surgical template, implant placement can be more accurate than free-hand operation. No significant difference is observed in the survival rate between template and free-hand.
{"title":"Comparison Between a Computer-Aided Surgical Template and the Free-Hand Method: A Systematic Review and Meta-Analysis.","authors":"Suya Chen, Qianmin Ou, Xuefeng Lin, Yan Wang","doi":"10.1097/ID.0000000000000915","DOIUrl":"https://doi.org/10.1097/ID.0000000000000915","url":null,"abstract":"<p><strong>Background: </strong>During implantation planning, dentists should be able to make an informed decision regarding whether to use an implant template to assist the surgery.</p><p><strong>Purpose: </strong>The aim of this meta-analysis was to assess the results of implantation with or without an implant template based on the accuracy, survival rate, and other considerations.</p><p><strong>Materials and methods: </strong>In January 2018, a systematic review was undertaken for randomized controlled trials and retrospective and prospective cohort studies with relevance to implant accuracy and the survival rate between the implant template and free-hand method. The odds ratios (ORs) of the survival rate and the mean difference of accuracy deviation from the selected papers were estimated by meta-analysis.</p><p><strong>Results: </strong>Of the 362 screened articles, 6 studies were included in the meta-analysis. Comparison of the survival rate of implant surgery with or without an implant template revealed no significant result (OR = 1.71, 95% confidence interval [CI] 0.65-4.51). Significant differences in accuracy were observed in angular (mean difference = -5.45 degrees, 95% CI -0.66 to -4.24 degrees) and apical deviation (mean difference = -0.83 mm, 95% CI -1.12 to -0.54).</p><p><strong>Conclusions: </strong>With the technology of computer-aided surgical template, implant placement can be more accurate than free-hand operation. No significant difference is observed in the survival rate between template and free-hand.</p>","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37340319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000937
S. Qi, Jinjin Wu, Yiwen Xu, Yiming Zhang, Raorao Wang, Kai Li, Yuanzhi Xu
PURPOSE The aim of this study is to investigate the biological activity and antibacterial property of cerium oxide-incorporated calcium silicate coatings (CeO2-CS) in dental implants. MATERIALS AND METHODS In this study, MC3T3-E1 cells cultured on the plastic, Ti-6Al-4V, and the cerium oxide-incorporated calcium silicate coatings (CeO2-CS) coating served as the blank, control, and CeO2-CS groups, respectively. A cell counting kit-8 (CCK-8) and flow cytometry were used to evaluate the biocompatibility. The osteoblastic differentiation of the MC3T3-E1 cells was also analyzed by quantitative real-time polymerase chain reaction analysis. The CCK-8 and counts of colony-forming units (CFUs) were used to detect the antibacterial activity of the coating on Enterococcus faecalis. The study showed that the cerium oxide-incorporated calcium silicate coating (CeO2-CS) has better biocompatibility. Meanwhile, the ALP, OCN, and BSP mRNA expression levels in the CeO2-CS group were significantly upregulated (P < 0.05). The number of viable bacteria and the CFU results were significantly reduced in the CeO2-CS group (P < 0.05). CONCLUSION The cerium oxide-incorporated calcium silicate coatings (CeO2-CS) may promote the osteoblastic differentiation of osteoblasts. Meanwhile, the cerium oxide-incorporated calcium silicate coating (CeO2-CS) showed strong antimicrobial activity on E. faecalis, with good biocompatibility.
{"title":"Chemical Stability and Antimicrobial Activity of Plasma-Sprayed Cerium Oxide-Incorporated Calcium Silicate Coating in Dental Implants.","authors":"S. Qi, Jinjin Wu, Yiwen Xu, Yiming Zhang, Raorao Wang, Kai Li, Yuanzhi Xu","doi":"10.1097/ID.0000000000000937","DOIUrl":"https://doi.org/10.1097/ID.0000000000000937","url":null,"abstract":"PURPOSE\u0000The aim of this study is to investigate the biological activity and antibacterial property of cerium oxide-incorporated calcium silicate coatings (CeO2-CS) in dental implants.\u0000\u0000\u0000MATERIALS AND METHODS\u0000In this study, MC3T3-E1 cells cultured on the plastic, Ti-6Al-4V, and the cerium oxide-incorporated calcium silicate coatings (CeO2-CS) coating served as the blank, control, and CeO2-CS groups, respectively. A cell counting kit-8 (CCK-8) and flow cytometry were used to evaluate the biocompatibility. The osteoblastic differentiation of the MC3T3-E1 cells was also analyzed by quantitative real-time polymerase chain reaction analysis. The CCK-8 and counts of colony-forming units (CFUs) were used to detect the antibacterial activity of the coating on Enterococcus faecalis. The study showed that the cerium oxide-incorporated calcium silicate coating (CeO2-CS) has better biocompatibility. Meanwhile, the ALP, OCN, and BSP mRNA expression levels in the CeO2-CS group were significantly upregulated (P < 0.05). The number of viable bacteria and the CFU results were significantly reduced in the CeO2-CS group (P < 0.05).\u0000\u0000\u0000CONCLUSION\u0000The cerium oxide-incorporated calcium silicate coatings (CeO2-CS) may promote the osteoblastic differentiation of osteoblasts. Meanwhile, the cerium oxide-incorporated calcium silicate coating (CeO2-CS) showed strong antimicrobial activity on E. faecalis, with good biocompatibility.","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49478975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/ID.0000000000000931
V. Perrotti, D. Zhang, Andrew Liang, Jonathan Wang, A. Quaranta
OBJECTIVES The primary aim of the present article was to review the effect and the clinical significance of abutment dis- and reconnection on the peri-implant marginal bone levels. MATERIALS AND METHODS English articles published from 2009 to April 2019 were identified on the MEDLINE, Cochrane Library, and PubMed databases, according to the PRISMA guidelines. Comparative in vivo studies on humans were included. RESULTS A total of 4 studies with different levels of bias were included in this review. A significant heterogeneity of the reported data was observed, which limited the comparison of the findings. The only parameter that was homogenous throughout all 4 studies was the marginal bone level measurement. CONCLUSION Within the limitations of the present review, it can be suggested that minimizing the number of abutment dis- and reconnections would be beneficial to ensure minimal disruption to the peri-implant tissue and marginal bone level. However, the clinical significance of the marginal bone level changes is still inconclusive.
{"title":"The Effect of One-Abutment at One-Time on Marginal Bone Loss Around Implants Placed in Healed Bone: A Systematic Review of Human Studies.","authors":"V. Perrotti, D. Zhang, Andrew Liang, Jonathan Wang, A. Quaranta","doi":"10.1097/ID.0000000000000931","DOIUrl":"https://doi.org/10.1097/ID.0000000000000931","url":null,"abstract":"OBJECTIVES\u0000The primary aim of the present article was to review the effect and the clinical significance of abutment dis- and reconnection on the peri-implant marginal bone levels.\u0000\u0000\u0000MATERIALS AND METHODS\u0000English articles published from 2009 to April 2019 were identified on the MEDLINE, Cochrane Library, and PubMed databases, according to the PRISMA guidelines. Comparative in vivo studies on humans were included.\u0000\u0000\u0000RESULTS\u0000A total of 4 studies with different levels of bias were included in this review. A significant heterogeneity of the reported data was observed, which limited the comparison of the findings. The only parameter that was homogenous throughout all 4 studies was the marginal bone level measurement.\u0000\u0000\u0000CONCLUSION\u0000Within the limitations of the present review, it can be suggested that minimizing the number of abutment dis- and reconnections would be beneficial to ensure minimal disruption to the peri-implant tissue and marginal bone level. However, the clinical significance of the marginal bone level changes is still inconclusive.","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000931","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41665444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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