Implant Dentistry最新文献

英文中文

The Editorial Council 编辑委员会

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2022-09-30 DOI: 10.1097/00008505-199312000-00003

Рахаев, А.И.

引用次数: 0

Clinical Implications of Functional Mitral Regurgitation Severity in Patients with Heart Failure with Reduced Ejection Fraction (HFrEF). 射血分数降低型心力衰竭（HFrEF）患者功能性二尖瓣反流严重程度的临床意义。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2022-02-01 DOI: 10.5455/medarh.2022.76.17-22

Nabil Naser

Background: An estimated 64.3 million people are living with heart failure worldwide. Functional MR in chronic HFrEF reflects primarily the severity of LV dysfunction and is not related to structural alterations of the mitral valvular apparatus. FMR in patients with HFrEF independently of the etiology of HFrEF and its underlying mechanisms, contributes to progression of the symptoms of HF and is independent predictor of worse clinical outcomes.Objective: The purpose of this study was to assess the severity of functional mitral regurgitation (FMR) and its clinical implications in patients with chronic heart failure with reduced ejection fraction (HFrEF).Methods: We enrolled 146 consecutive adult patients with CHF with reduced ejection fraction (HFrEF) who presented to outpatient clinics. All patients underwent clinical and physical examination. Baseline examination included medical history, detailed assessment of current medication, electrocardiogram recording, transthoracic echocardiogram and comorbidities. Heart failure with reduced ejection fraction was defined in line with the new guidelines as history of HF signs and symptoms as well as a LV ejection fraction (LVEF) below 40%. Cardiovascular risk factors were recorded according to the respective guidelines. FMR was defined and graded according to the ESC/EACTS Guidelines for the management of valvular heart disease. The extent of FMR was assessed at baseline and after a median follow-up period of 4 years in 146 consecutive HFrEF patients (left ventricular ejection fraction <40%). All of the patients received the heart failure (HF) medications in agreement with 2016 and 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Major adverse cardiac events were defined as a composite of all-cause death and the need for admission for HF.Results: A total of 146 chronic HFrEF patients (mean age of 63±11 years, 62% male, mean LVEF of 25±11%) of which 19% patients had severe FMR at baseline, with a mean EROA of 31.4±2.7 mm2 and a mean Reg Vol of 45.9±5.3 ml. There was a significant interaction between FMR and NYHA functional class in predicting death or need for hospitalization, (P < 0.0001 for the interaction term FMR NYHA III-IV). During a median follow-up period of 4.2 (IQR) 3.1-5.8) years, the primary endpoint occurred in 52 (36%) patients (21 HF admissions, and 31 deaths). There was a strong graded association between the presence and degree of FMR and risk of death or admission (P <0.0001) at 4 years follow-up period. Regarding HF therapy, 129 patients (88%) received RAAS antagonists, 17 patients (12%) received ARNI, 86 patients (59%) received beta-blockers, 75 patients (51%) were treated with MRA. 31 patients (21%) underwent cardiac resynchronization therapy (CRT) with a response rate of 64%. 24 patients (16%) underwent ICD implantation.Conclusion:

背景：全球估计有 6430 万人患有心力衰竭。慢性心力衰竭患者的功能性 MR 主要反映左心室功能障碍的严重程度，与二尖瓣装置的结构改变无关。独立于 HFrEF 病因及其潜在机制的 HFrEF 患者功能性 MR 会导致 HF 症状恶化，并且是临床预后恶化的独立预测因子：本研究旨在评估射血分数降低的慢性心力衰竭（HFrEF）患者功能性二尖瓣反流（FMR）的严重程度及其临床影响：我们连续招募了 146 名到门诊就诊的射血分数降低型慢性心力衰竭（HFrEF）成年患者。所有患者均接受了临床和体格检查。基线检查包括病史、当前用药的详细评估、心电图记录、经胸超声心动图和合并症。根据新指南，射血分数降低型心力衰竭的定义为：有心力衰竭症状和体征，左心室射血分数（LVEF）低于40%。心血管风险因素根据相关指南进行记录。FMR根据ESC/EACTS瓣膜性心脏病管理指南进行定义和分级。对 146 名连续的 HFrEF 患者（左心室射血分数结果）在基线和中位随访 4 年后的 FMR 程度进行了评估：共有 146 名慢性 HFrEF 患者（平均年龄为 63±11 岁，62% 为男性，平均 LVEF 为 25±11%），其中 19% 的患者在基线时患有严重的 FMR，平均 EROA 为 31.4±2.7 mm2，平均 Reg Vol 为 45.9±5.3 ml。在预测死亡或住院需求方面，FMR 和 NYHA 功能分级之间存在明显的交互作用（交互作用项 FMR NYHA III-IV P < 0.0001）。在中位随访 4.2（IQR）3.1-5.8 年期间，52 例（36%）患者（21 例高血压入院，31 例死亡）出现了主要终点。）FMR 的存在和程度与死亡或入院风险之间存在很强的分级关联（P 结论：FMR 的存在和程度与死亡或入院风险之间存在很强的分级关联：对于同时患有 FMR 的慢性心房颤动患者，指导性药物治疗是一线治疗方法。在这种一线治疗方法之后，对于持续存在严重症状的 FMR 患者，可以考虑手术或 MitraClip 经导管治疗，以改善症状、生活质量和功能状态。

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引用次数: 0

Implant. 植体。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2020-02-07 DOI: 10.1007/1-4020-0613-6_8693

Andrew Gazerro

引用次数: 10

Prosthetic Rehabilitation of the Posterior Atrophic Maxilla, Short (≤6 mm) or Long (≥10 mm) Dental Implants? A Systematic Review, Meta-analysis, and Trial Sequential Analysis: Naples Consensus Report Working Group A. 后萎缩上颌，短(≤6mm)或长(≥10mm)种植体的修复修复?系统评价、荟萃分析和试验序列分析:那不勒斯共识报告A工作组。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/ID.0000000000000919

Andrea Ravidà, I-Ching Wang, Gilberto Sammartino, Shayan Barootchi, Mustafa Tattan, Giuseppe Troiano, Luigi Laino, Gaetano Marenzi, Ugo Covani, Hom-Lay Wang

Purpose: To compare the clinical and patient-reported outcomes of ≤6-mm implants with those of ≥10-mm implants placed after both lateral and transcrestal sinus floor elevation.

Materials and methods: Using PubMed (MEDLINE), EMBASE, and Cochrane, a literature search for randomized controlled trials was performed. All the outcome variables were evaluated through a quantitative meta-analysis, and the influence of other clinical covariates were determined with a metaregression. For the survival outcomes, trial sequential analysis (TSA) was performed to adjust results for type I and II errors and to analyze the power of the available evidence.

Results: After full-text reading, 12 studies were included in the analyses. No statistically significant difference was found after 3 years between the 2 study groups (P = 0.36). Short implants displayed fewer biological complications (P = 0.05), less marginal bone loss (MBL) from implant placement (P < 0.01), and reduced surgical time and treatment cost. However, long implants showed a statistically significant smaller number of prosthetic complications (P = 0.03). TSA confirmed the results of the meta-analysis, revealing that additional studies are needed due to low statistical power of the available evidence.

Conclusion: The placement of short implants is a predictable option in treating patients with maxillary atrophy up to a 3-year follow-up. Studies with a longer observational period are needed to study the long-term performance of these implants.

目的:比较≤6mm种植体与≥10mm种植体在侧位和经瓣窦底提升后的临床和患者报告的结果。材料和方法:使用PubMed (MEDLINE)、EMBASE和Cochrane进行随机对照试验的文献检索。通过定量荟萃分析评估所有结局变量，并通过meta回归确定其他临床协变量的影响。对于生存结果，进行试验序列分析(TSA)以调整I型和II型错误的结果，并分析现有证据的有效性。结果:经全文阅读后，12项研究被纳入分析。3年后，两组间差异无统计学意义(P = 0.36)。短种植体的生物学并发症较少(P = 0.05)，种植体的边缘骨丢失(MBL)较少(P < 0.01)，减少了手术时间和治疗费用。然而，长假体的假体并发症较少，差异有统计学意义(P = 0.03)。运输安全管理局证实了荟萃分析的结果，表明由于现有证据的统计效力较低，需要进行更多的研究。结论:放置短种植体是治疗上颌萎缩患者的一种可预测的选择，随访时间长达3年。需要更长的观察期来研究这些植入物的长期性能。

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引用次数: 23

Misch's Contemporary Implant Dentistry 米施的当代种植牙科

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/id.0000000000000951

G. Christensen

引用次数: 22

2019 Concluding Editorial. 2019年总结社论。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/id.0000000000000946

K. Judy

引用次数: 0

Fifteen-Year Follow-up of Short Dental Implants in the Completely Edentulous Jaw: Submerged Versus Nonsubmerged Healing. 全无牙颌短牙种植体的15年随访:浸入式与非浸入式愈合。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/ID.0000000000000935

E. Anitua, M. Alkhraisat

PURPOSEShort implants are a minimally invasive alternative in the management of alveolar bone atrophy. This study aimed to assess the influence of the surgical approach (1-stage vs 2-stage) on the 15-year survival and marginal bone loss of short implants in a fixed complete denture.MATERIALS AND METHODSA retrospective clinical study was conducted in a single private dental clinic that included short implants placed between January 2001 and December 2002.RESULTSForty-one short implants supported 18 screw-retained complete dentures. The mean follow-up time was 15 ± 3 years. The surgical approach (1-stage vs 2-stage) did not significantly affect implant survival and marginal bone loss. The implant survival rate was 90.2%.CONCLUSIONSShort dental implants could be predictably indicated to support fixed complete dentures. The implants could be placed through a 1- or 2-stage surgery.

目的:短种植体是治疗牙槽骨萎缩的一种微创方法。本研究旨在评估手术入路(1期vs 2期)对固定全口义齿短种植体15年生存率和边缘骨丢失的影响。材料与方法回顾性临床研究于2001年1月至2002年12月在一家私人牙科诊所进行。结果41个短种植体支撑18个螺钉固位全口义齿。平均随访时间15±3年。手术入路(一期vs二期)对种植体存活和边缘骨丢失没有显著影响。种植体成活率为90.2%。结论短种植体可预见地支持固定全口义齿。植入物可以通过1到2个阶段的手术植入。

引用次数: 6

Ridge Augmentation Comparing an Allograft Plus Autogenous Bone Chips to an Osteoinductive Demineralized Bone Matrix: A Clinical and Histologic Study in Humans. 异体骨移植加自体骨芯片与骨诱导脱矿骨基质的比较:人类临床和组织学研究。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/ID.0000000000000925

Abhishek Patel, Henry Greenwell, Margaret Hill, Brian Shumway, Aaron Radmall

Purpose: The primary aim of this randomized, controlled, blinded, clinical trial was to compare a mix of particulate allograft and harvested autogenous particles (Autogenous) to an osteoinductive demineralized bone matrix (DBM) allograft on clinical and histologic outcomes for horizontal ridge augmentation procedure.

Materials and methods: Fourteen patients with a horizontal ridge defect with at least 1 adjacent tooth were entered into this study. The test group of 7 subjects received corticocancellous particulate allograft (Mineross) mixed with autogenous bone chips (70:30) harvested using a bone scraper (SafeScraper TWIST). Seven subjects in the control group received DBM (Optecure-CCC). Both groups had a corticocancellous particulate allograft overlay and an acellular dermis membrane (ADMG) (AlloDerm GBR) to cover the grafts.

Results: For the Autogenous group, there was a gain of 3.5 ± 1.4 mm while the DBM group gained 3.8 ± 1.6 mm (P < 0.05). Vertical change was minimal for both groups (P > 0.05). The Autogenous group had a mean of 35% vital bone while the DBM had 39% (P > 0.05).

Conclusions: Both treatments provided similar gain of ridge width and minimal loss of ridge height. The autogenous bone chips did not provide any additional benefit when compared with allograft alone that had lot verified osteoinductive activity.

目的:这项随机、对照、盲法临床试验的主要目的是比较颗粒同种异体移植物和收获的自体颗粒(自体)与骨诱导脱矿骨基质(DBM)同种异体移植物在水平嵴增强手术中的临床和组织学结果。材料与方法:选取14例水平牙脊缺损伴至少1颗邻牙的患者为研究对象。试验组7名受试者接受皮质松质颗粒同种异体移植物(Mineross)与自体骨片(70:30)混合，使用骨刮板(SafeScraper TWIST)采集。对照组7例接受DBM (Optecure-CCC)治疗。两组均有皮质松质颗粒异体移植物覆盖层和脱细胞真皮膜(ADMG) (AlloDerm GBR)覆盖移植物。结果:自体组增厚3.5±1.4 mm, DBM组增厚3.8±1.6 mm (P < 0.05)。两组的垂直变化最小(P > 0.05)。自体组平均存活骨35%，DBM组平均存活骨39% (P > 0.05)。结论:两种治疗方法均可获得相似的脊宽增益和最小的脊高损失。与同种异体骨片相比，自体骨片没有提供任何额外的益处，而同种异体骨片具有许多已证实的骨诱导活性。

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引用次数: 5

Comparison Between a Computer-Aided Surgical Template and the Free-Hand Method: A Systematic Review and Meta-Analysis. 计算机辅助手术模板与徒手手术方法的比较:系统回顾和荟萃分析。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/ID.0000000000000915

Suya Chen, Qianmin Ou, Xuefeng Lin, Yan Wang

Background: During implantation planning, dentists should be able to make an informed decision regarding whether to use an implant template to assist the surgery.

Purpose: The aim of this meta-analysis was to assess the results of implantation with or without an implant template based on the accuracy, survival rate, and other considerations.

Materials and methods: In January 2018, a systematic review was undertaken for randomized controlled trials and retrospective and prospective cohort studies with relevance to implant accuracy and the survival rate between the implant template and free-hand method. The odds ratios (ORs) of the survival rate and the mean difference of accuracy deviation from the selected papers were estimated by meta-analysis.

Results: Of the 362 screened articles, 6 studies were included in the meta-analysis. Comparison of the survival rate of implant surgery with or without an implant template revealed no significant result (OR = 1.71, 95% confidence interval [CI] 0.65-4.51). Significant differences in accuracy were observed in angular (mean difference = -5.45 degrees, 95% CI -0.66 to -4.24 degrees) and apical deviation (mean difference = -0.83 mm, 95% CI -1.12 to -0.54).

Conclusions: With the technology of computer-aided surgical template, implant placement can be more accurate than free-hand operation. No significant difference is observed in the survival rate between template and free-hand.

背景:在种植计划期间，牙医应该能够就是否使用种植模板来辅助手术做出明智的决定。目的:本荟萃分析的目的是基于准确性、存活率和其他考虑因素来评估植入或不植入模板的结果。材料与方法:2018年1月，系统回顾了随机对照试验、回顾性和前瞻性队列研究对种植体模板与徒手法种植体准确性和存活率的影响。通过荟萃分析估计入选文献的生存率的优势比(ORs)和准确度偏差的平均差异。结果:在筛选的362篇文章中，有6篇研究被纳入meta分析。使用或不使用种植模板的种植体手术生存率比较无显著差异(or = 1.71, 95%可信区间[CI] 0.65-4.51)。在角度(平均差值= -5.45度，95% CI为-0.66至-4.24度)和根尖偏差(平均差值= -0.83 mm, 95% CI为-1.12至-0.54)上观察到准确性的显著差异。结论:采用计算机辅助手术模板技术，种植体植入比徒手操作更准确。模板组与徒手组存活率无显著差异。

{"title":"Comparison Between a Computer-Aided Surgical Template and the Free-Hand Method: A Systematic Review and Meta-Analysis.","authors":"Suya Chen, Qianmin Ou, Xuefeng Lin, Yan Wang","doi":"10.1097/ID.0000000000000915","DOIUrl":"https://doi.org/10.1097/ID.0000000000000915","url":null,"abstract":"Background: During implantation planning, dentists should be able to make an informed decision regarding whether to use an implant template to assist the surgery.Purpose: The aim of this meta-analysis was to assess the results of implantation with or without an implant template based on the accuracy, survival rate, and other considerations.Materials and methods: In January 2018, a systematic review was undertaken for randomized controlled trials and retrospective and prospective cohort studies with relevance to implant accuracy and the survival rate between the implant template and free-hand method. The odds ratios (ORs) of the survival rate and the mean difference of accuracy deviation from the selected papers were estimated by meta-analysis.Results: Of the 362 screened articles, 6 studies were included in the meta-analysis. Comparison of the survival rate of implant surgery with or without an implant template revealed no significant result (OR = 1.71, 95% confidence interval [CI] 0.65-4.51). Significant differences in accuracy were observed in angular (mean difference = -5.45 degrees, 95% CI -0.66 to -4.24 degrees) and apical deviation (mean difference = -0.83 mm, 95% CI -1.12 to -0.54).Conclusions: With the technology of computer-aided surgical template, implant placement can be more accurate than free-hand operation. No significant difference is observed in the survival rate between template and free-hand.","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":"28 6","pages":"578-589"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37340319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Chemical Stability and Antimicrobial Activity of Plasma-Sprayed Cerium Oxide-Incorporated Calcium Silicate Coating in Dental Implants. 牙科植入物中等离子喷涂氧化铈结合硅酸钙涂层的化学稳定性和抗菌活性。

3区医学 Q1 Dentistry

Implant Dentistry

Pub Date : 2019-12-01 DOI: 10.1097/ID.0000000000000937

S. Qi, Jinjin Wu, Yiwen Xu, Yiming Zhang, Raorao Wang, Kai Li, Yuanzhi Xu

PURPOSEThe aim of this study is to investigate the biological activity and antibacterial property of cerium oxide-incorporated calcium silicate coatings (CeO2-CS) in dental implants.MATERIALS AND METHODSIn this study, MC3T3-E1 cells cultured on the plastic, Ti-6Al-4V, and the cerium oxide-incorporated calcium silicate coatings (CeO2-CS) coating served as the blank, control, and CeO2-CS groups, respectively. A cell counting kit-8 (CCK-8) and flow cytometry were used to evaluate the biocompatibility. The osteoblastic differentiation of the MC3T3-E1 cells was also analyzed by quantitative real-time polymerase chain reaction analysis. The CCK-8 and counts of colony-forming units (CFUs) were used to detect the antibacterial activity of the coating on Enterococcus faecalis. The study showed that the cerium oxide-incorporated calcium silicate coating (CeO2-CS) has better biocompatibility. Meanwhile, the ALP, OCN, and BSP mRNA expression levels in the CeO2-CS group were significantly upregulated (P < 0.05). The number of viable bacteria and the CFU results were significantly reduced in the CeO2-CS group (P < 0.05).CONCLUSIONThe cerium oxide-incorporated calcium silicate coatings (CeO2-CS) may promote the osteoblastic differentiation of osteoblasts. Meanwhile, the cerium oxide-incorporated calcium silicate coating (CeO2-CS) showed strong antimicrobial activity on E. faecalis, with good biocompatibility.

目的本研究的目的是研究掺入氧化铈的硅酸钙涂层（CeO2-CS）在种植牙中的生物活性和抗菌性能。材料和方法在本研究中，在塑料、Ti-6Al-4V和掺有氧化铈的硅酸钙涂层（CeO2-CS）上培养的MC3T3-E1细胞分别作为空白组、对照组和CeO2-CS组。采用细胞计数试剂盒-8（CCK-8）和流式细胞仪对其生物相容性进行评价。MC3T3-E1细胞的成骨细胞分化也通过定量实时聚合酶链反应分析进行分析。使用CCK-8和菌落形成单位计数（CFU）来检测涂层对粪肠球菌的抗菌活性。研究表明，掺入氧化铈的硅酸钙涂层具有较好的生物相容性。同时，CeO2-CS组ALP、OCN和BSP mRNA表达水平显著上调（P<0.05），活菌数和CFU结果显著降低（P<0.05）。同时，掺入氧化铈的硅酸钙涂层（CeO2-CS）对粪肠球菌具有较强的抗菌活性，具有良好的生物相容性。

{"title":"Chemical Stability and Antimicrobial Activity of Plasma-Sprayed Cerium Oxide-Incorporated Calcium Silicate Coating in Dental Implants.","authors":"S. Qi, Jinjin Wu, Yiwen Xu, Yiming Zhang, Raorao Wang, Kai Li, Yuanzhi Xu","doi":"10.1097/ID.0000000000000937","DOIUrl":"https://doi.org/10.1097/ID.0000000000000937","url":null,"abstract":"PURPOSE\u0000The aim of this study is to investigate the biological activity and antibacterial property of cerium oxide-incorporated calcium silicate coatings (CeO2-CS) in dental implants.\u0000\u0000\u0000MATERIALS AND METHODS\u0000In this study, MC3T3-E1 cells cultured on the plastic, Ti-6Al-4V, and the cerium oxide-incorporated calcium silicate coatings (CeO2-CS) coating served as the blank, control, and CeO2-CS groups, respectively. A cell counting kit-8 (CCK-8) and flow cytometry were used to evaluate the biocompatibility. The osteoblastic differentiation of the MC3T3-E1 cells was also analyzed by quantitative real-time polymerase chain reaction analysis. The CCK-8 and counts of colony-forming units (CFUs) were used to detect the antibacterial activity of the coating on Enterococcus faecalis. The study showed that the cerium oxide-incorporated calcium silicate coating (CeO2-CS) has better biocompatibility. Meanwhile, the ALP, OCN, and BSP mRNA expression levels in the CeO2-CS group were significantly upregulated (P < 0.05). The number of viable bacteria and the CFU results were significantly reduced in the CeO2-CS group (P < 0.05).\u0000\u0000\u0000CONCLUSION\u0000The cerium oxide-incorporated calcium silicate coatings (CeO2-CS) may promote the osteoblastic differentiation of osteoblasts. Meanwhile, the cerium oxide-incorporated calcium silicate coating (CeO2-CS) showed strong antimicrobial activity on E. faecalis, with good biocompatibility.","PeriodicalId":13309,"journal":{"name":"Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/ID.0000000000000937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49478975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

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