Investigation of Antibiotics Residues in Imported and Locally Produced Red Meat in Muscat, Sultanate of Oman

S. Al-Kindi, A. Ahuja, Razna Almaimani, Siham Khamis Al-Mamari, M. Al-Balushi
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Abstract

Background: Antibiotics are heavily used for animal treatment, growth enhancer and protection from disease. The residues of antibiotics are related to antibiotic resistance which is the biggest threats to global health, food security and development today. The aim of this study was to investigate the presence of antibiotic residues in available red meat in the Sultanate of Oman. Methods: The extraction was done using QuEChERS method by Aglient and 11 standards were used. The extract was analyzed using The Aglient 6460 LC-MS/MS. Result: The results showed that investigated Omani goat muscle and liver were free of antibiotics as latter they used as blank sample. All investigated Somali goat samples didn’t contain Tetracycline, Amoxicillin, Ceftiofur, Oxacillin, Deoxytetracline, Tylosin and Phenoxymethylpenicillin. Only two samples had Tilmicosin with value of 18-32.2 µl/kg which was that was lower than maxiumam residual limit (MRL). Around 48% of total somali goat samples contained Oxytetracycline (OXY) and Chlorotetracycline (CTC) with value lower than MRL. However, two samples had values of CTC and OXY exceeding the MRL. Ciprofloxacin and Enrofloxacine were detected in 9 samples exceeding the MRL. The finding of this study showed unsafe food source supply to Oman as detection of antibiotic residues in meat.
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阿曼苏丹国马斯喀特进口和本地生产的红肉中抗生素残留调查
背景:抗生素被大量用于动物治疗、促进生长和预防疾病。抗生素残留与抗生素耐药性有关,抗生素耐药性是当今全球健康、粮食安全和发展面临的最大威胁。本研究的目的是调查在阿曼苏丹国可用的红肉中抗生素残留的存在。方法:采用QuEChERS提取法,采用Aglient提取11种标准品。提取液采用The Aglient 6460 LC-MS/MS进行分析。结果:所调查阿曼山羊的肌肉和肝脏作为空白样品均不含抗生素。所有被调查的索马里山羊样品均不含四环素、阿莫西林、头孢替弗、奥西林、脱氧四环素、泰洛辛和苯氧甲基青霉素。仅有2份样品中Tilmicosin含量为18 ~ 32.2µl/kg,低于最大残留限量(MRL)。索马里山羊总样品中约48%含有土霉素(OXY)和氯四环素(CTC),其值低于MRL。然而,两个样品的CTC和OXY值超过了MRL。9份样品中检出环丙沙星和恩诺沙星超过MRL。本研究结果显示,供应阿曼的不安全食物来源在肉类中检测到抗生素残留。
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