Tooth agenesis: genes and syndromic diseases –literature review

Abstract

Introduction and Objective. Tooth agenesis may be present even in 9.6% of individuals of both genders, with the predominance in permanent dentition. The aim of the study was to present a review of the literature on the etiology of dental agenesis, with particular emphasis on the genetic background and the associated syndromes of congenital abnormalities. Objective and Review Methods. Online databases were searched: Pubmed, GoogleScholar and Scopus. 32 articles from the last 18 years were qualified for the study and used in this review. Inclusion criteria were: children, congenital disorders, syndromic diseases, missing teeth, tooth agenesis. The study takes into account both syndromes common in the population and rare disorders.