A hexacationic coordination compound from Co(II) and a cationic ligand derived from 4,4ʹ-bipyridine: Synthesis, characterization and investigation for biological application
{"title":"A hexacationic coordination compound from Co(II) and a cationic ligand derived from 4,4ʹ-bipyridine: Synthesis, characterization and investigation for biological application","authors":"Atakilt Abebe, Getinet Tamiru","doi":"10.1080/23312009.2018.1564162","DOIUrl":null,"url":null,"abstract":"Abstract A hexapositively charged tetrahedral geometry Co(II) complex was synthesized using a new positively charged ligand prepared quaternizing 4,4ʹ-bipyridine by 1-bromobutane. It is characterized by spectrometry (1H NMR, ESI MS, Uv-Vis, ICP OES), carbon, hydrogen and nitrogen (CHN) elemental analysis, halide estimation and conductivity measurement. The complex showed significantly high molar conductivity value in water (640.83 S mol−1 cm2). Its in vitro biological activities were tested on one gram-positive (Staphylococcus aureus) and one gram-negative (Klebsiella pneumoniae) bacteria. It was found active against both bacteria with improved and better activity against the latter.","PeriodicalId":10640,"journal":{"name":"Cogent Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23312009.2018.1564162","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cogent Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/23312009.2018.1564162","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Abstract A hexapositively charged tetrahedral geometry Co(II) complex was synthesized using a new positively charged ligand prepared quaternizing 4,4ʹ-bipyridine by 1-bromobutane. It is characterized by spectrometry (1H NMR, ESI MS, Uv-Vis, ICP OES), carbon, hydrogen and nitrogen (CHN) elemental analysis, halide estimation and conductivity measurement. The complex showed significantly high molar conductivity value in water (640.83 S mol−1 cm2). Its in vitro biological activities were tested on one gram-positive (Staphylococcus aureus) and one gram-negative (Klebsiella pneumoniae) bacteria. It was found active against both bacteria with improved and better activity against the latter.
摘要以1-溴丁烷为原料，以4,4′-联吡啶为季铵化剂制备了一种带正电荷的新型配体，合成了六正电荷的四面体Co(II)配合物。通过光谱分析(1H NMR, ESI MS, Uv-Vis, ICP OES)，碳、氢、氮(CHN)元素分析，卤化物估算和电导率测量对其进行了表征。配合物在水中表现出较高的摩尔电导率值(640.83 S mol−1 cm2)。对一种革兰氏阳性菌(金黄色葡萄球菌)和一种革兰氏阴性菌(肺炎克雷伯菌)进行了体外生物活性测试。发现它对两种细菌都有活性，对后者的活性更强。
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
