{"title":"Carcinoma of Unknown Primary: Diagnostic Approaches for Radiologists","authors":"J.C. Junn, K.A. Soderlund, C. Glastonbury","doi":"10.3174/ng.2100031","DOIUrl":null,"url":null,"abstract":"Carcinoma of unknown primary is an important and complex disease entity that presents challenges to interpreting radiologists. This article presents a comprehensive clinical, pathologic, and radiologic work-up and assessment for radiologists. It is important for the radiologist to know\n the p16, high-risk human papilloma virus, and Epstein-Barr virus status; nodal drainage patterns of head and neck squamous cell carcinoma; and the utility of various imaging modalities to help identify the primary site and guide therapy.Learning Objectives: To understand the clinical,\n pathologic, and radiologic evaluation of carcinoma of unknown primary (CUP); to provide an overview of the clinical and pathologic work-up for CUP that aids in imaging interpretation; and to recognize patterns of nodal involvement for identification of the primary disease","PeriodicalId":36193,"journal":{"name":"Neurographics","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurographics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3174/ng.2100031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Carcinoma of unknown primary is an important and complex disease entity that presents challenges to interpreting radiologists. This article presents a comprehensive clinical, pathologic, and radiologic work-up and assessment for radiologists. It is important for the radiologist to know
the p16, high-risk human papilloma virus, and Epstein-Barr virus status; nodal drainage patterns of head and neck squamous cell carcinoma; and the utility of various imaging modalities to help identify the primary site and guide therapy.Learning Objectives: To understand the clinical,
pathologic, and radiologic evaluation of carcinoma of unknown primary (CUP); to provide an overview of the clinical and pathologic work-up for CUP that aids in imaging interpretation; and to recognize patterns of nodal involvement for identification of the primary disease
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