Preliminary physicochemical evaluation of Kushta-e-Aahar Mohra: A unique formulation of Unani medicine

Abstract

Introduction: Zahar Mohra (Serpentine/Bezoar stone) is mentioned as efficacious and a useful drug indicated in heart diseases in Unani medicine. It is also used to remove effect of poison and is termed in Unani Medicine as Daf-e-Zahar or Fad-e-Zahar (antidote). It acts as preservative of quwa (faculty) and ruh (pneuma). Unani physicians commonly use Zahar Mohra (ZM) in Kushta (Calcined) form, because the Kushta gives quick and potent response. In this work owing to its beneficial and efficacious use, Kushta-e-Zahar Mohra (KZM) was prepared as per contemporary methods and was subjected to preliminary physicochemical analysis to develop a standard. Materials and Methods: KZM was prepared as per contemporary method (Muffle furnace) by simulation of the heat pattern as per classical texts/method and its physico-chemical and instrumental analysis including XRD, ICP-MS and AAS was performed. Statistical analysis used was Mean ± SEM. Results: Prepared Kushta passes the classical Unani specification tests, contemporary test data for various physicochemical parameters were also set in. XRD analysis indicated presence of Mg2Si O4 (Magnesium Silicate) and Ca (Cl O)2. 3H2O (Calcium Chlorite Hydrate) phase. Conclusions: The study indicates content and physicochemical standards of KZM prepared by contemporary method; it can be a better choice. KZM can be safe for use as acclaimed for heart diseases in Unani System of Medicine.