Utilization of ActiGraft, an Autologous (Blood Clot) Graft in the Reconstruction of Soft Tissue Deficit from Hand Trauma – A Case Study

Abstract

The reconstruction of complex soft tissue deficits is associated with great difficulty. When treating intricate structures of the hand, optimal reconstruction is necessary to preserve the function and aesthetics of the hand, preferably to the level associated with preinjury. The mechanism of scar formation is a process that is targeted by many researchers in an attempt to lessen both clinical and financial burden. Excessive hypertrophic tissue can cause adverse events, such as obstruction of vital structures, tendons and nerves, which can reduce the overall function of the hand and the patient’s quality of life. ActiGraft, an autologous blood clot, provides effective wound healing and reconstruction of soft tissue, whilst mitigating hypertrophic scar tissue. ActiGraft expedited the process of revitalization of the wound by promoting ingrowth of healthy granulation tissue and reduction in excessive scar tissue formation. Here we present a case of ActiGraft treatment utilized weekly to promote soft tissue reconstruction of the hand, as well as modification of the mechanism required for scar tissue accumulation. Blood was withdrawn from the patient, at the point-of-care, to create a blood clot that was applied to the wound area. This treatment exhibited significant promotion of granulation tissue ingrowth, repairing the injured soft tissue and skin deficit. ActiGraft was found to be a cost-effective treatment that provided optimal and effective healing of the deficit related to the trauma of the hand.