Correlation Of Pulmonary Function Abnormalities With Serum Lipids And Physical Parameters

Q3 Pharmacology, Toxicology and Pharmaceutics Journal of Pharmaceutical Negative Results Pub Date : 2023-01-06 DOI:10.47750/pnr.2022.13.s09.908
Tushar Vishnu Tonde , Rahul S Patil , Swapnil Sure
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Abstract

Background: Globally obesity rates have more than doubled since 1980 from 5% to 10% in men and 8% to 14% in women. At least 2.8 million people die each year globally, as a result of being overweight or obese. Objective: to study correlation of pulmonary function abnormalities with Serum Lipids and Physical Parameters. Materials & Methods: This was a prospective study done on 40 obese patients during the period from January to December 2012 attending to the Dr. D. Y. Patil Hospital, Mumbai. Results: Obesity is associated with decreased FVC, FEV1, MMEFR, and Restrictive Pattern of PFT. Obese individuals who have undesirable range of hypercholesterolemia tend to have restrictive pattern of pulmonary function test. Undesirable range of hypertriglyceridemia is not associated with any significant abnormality. Body Indices and duration of obesity do not have any significant correlation with lung volumes. Conclusion: It was concluded that Obesity is associated with decreased forced vital capacity. Body mass index, waist hip ratio and triceps fold thickness do not have any significant correlation with lung volumes.
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肺功能异常与血脂、体质参数的相关性
背景:自1980年以来,全球肥胖率翻了一番多,男性从5%上升到10%,女性从8%上升到14%。全球每年至少有280万人因超重或肥胖而死亡。目的:探讨肺功能异常与血脂、体质参数的相关性。材料与方法:这是一项前瞻性研究,对2012年1月至12月期间在孟买D.Y.Patil医生医院就诊的40名肥胖患者进行了研究。结果:肥胖与FVC、FEV1、MMEFR和PFT限制型降低有关。患有高胆固醇血症的肥胖者往往具有限制性的肺功能测试模式。高甘油三酯血症的不良范围与任何显著异常无关。身体指数和肥胖持续时间与肺容量没有任何显著相关性。结论:肥胖与强迫肺活量下降有关。体重指数、腰臀比和三头肌折叠厚度与肺容量无显著相关性。
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