In vitro Antibacterial Potential of the Oleoresin, Leaf Crude Hydroalcoholic Extracts and Isolated Compounds of the Copaifera spp. Against Helicobacter pylori

IF 0.9 Q4 CHEMISTRY, MEDICINAL Journal of Biologically Active Products from Nature Pub Date : 2021-03-04 DOI:10.1080/22311866.2021.1914730

T. S. Moraes, Lucas Kozoski de Lima, R. Veneziani, S. Ambrósio, R. Santos, J. J. M. Silva, Gustavo Lima Ribeiro, J. Bastos, C. Martins

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引用次数: 3

Abstract

Abstract Helicobacter pylori is often related to severe clinical manifestations of infections and may increase an individual’s chance of developing stomach cancer. We are reporting the in vitro anti-H. pylori effects of several Copaifera spp. derivatives such as oleoresins, hydroalcoholic crude extracts from the leaves, and isolated compounds, by determining their Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values. It was obtained promising MIC (MBC) values, ranging from 6.25 (12.5) to 100 (400) μg/mL, from 12.5 (25) to 100 (100) μg/mL, and from 3.12 (3.12) to 100 (100) μg/mL respectively, for Copaifera spp. oleoresins, leave crude hydroalcoholic extracts and isolated compounds. Therefore, all Copaifera spp. derivatives displayed promising antibacterial activities against H. pylori.

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黄花楸油树脂、叶粗水醇提取物及分离化合物对幽门螺杆菌的体外抑菌活性研究

摘要幽门螺杆菌通常与感染的严重临床表现有关，并可能增加个体患癌症的机会。我们正在报道体外抗H。几种Copaifera spp.衍生物，如油树脂、叶片的水醇粗提取物和分离的化合物的幽门螺杆菌效应，通过测定它们的最小抑制浓度（MIC）和最小杀菌浓度（MBC）值。对于Copaifera spp.油树脂，其MIC（MBC）值为6.25（12.5）至100（400）μg/mL，12.5（25）至100。因此，所有Copaifera spp.衍生物对幽门螺杆菌都显示出良好的抗菌活性。

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来源期刊

Journal of Biologically Active Products from Nature Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)

CiteScore

2.10

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0.00%

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