The Latest Evidence on the Association Between Vitamins and Non-alcoholic Fatty Liver Disease in Childhood

Abstract

Context: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in children, with an increased incidence of overweight and obesity. Currently, no food and drug administration is approved for treating NAFLD in children; however, antioxidants such as vitamins are the safest options for managing this disease. Regarding the unknown aspects of managing NAFLD, this review provides an overview of the latest evidence on the association of vitamins A, B, C, D, and E with NAFLD in children and adolescents. Evidence Acquisition: In this narrative review, we searched and extracted relevant English publications from the Web of Science, PubMed, Scopus, and Google Scholar using keywords such as non-alcoholic fatty liver disease, NAFLD, children, pediatric, Vitamin A, Vitamin B, Vitamin C, Vitamin D, and Vitamin E. Results: The level of vitamins A, B, C, D, and E in children with NAFLD has been linked to the disease’s prognosis and severity. Conclusions: Regarding previous studies on this issue, measuring vitamins in children with NAFLD seems logical.