Age-Dependent Comparative Study of 4 Hz and 8 Hz EMF Exposure on Heart Muscle Tissue Hydration of Rats

生物物理学期刊(英文) Pub Date : 2019-01-17 DOI:10.4236/OJBIPHY.2019.91005

Lilia Narinyan, S. Ayrapetyan

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引用次数: 1

Abstract

Previously we have shown that 4 Hz and 8 Hz EMF exposures have depressing effect on the thermodynamic activity of water, which decreases peroxide formation. It has also been shown that 4 Hz EMF-treated physiological solution modulates the growth and development of microbes and heart muscle contractility, but 8 Hz EMF has pronounced inhibitory effect on bacterial growth and development. Therefore, in order to elucidate the possible mechanism of 4 Hz and 8 Hz EMF effects on heart muscle function, in the present work the effects of 4 Hz and 8 Hz EMF exposures on heart muscle tissue hydration, the sensitivity of 4 Hz and 8 Hz EMF-induced tissue hydration to 10−4 M ouabain (Na+/K+ pump inhibition) and 10−9 M ouabain (activation of intracellular signaling system) as well as the effects of 4 Hz and 8 Hz EMF exposures on the number of Na+/K+ pump units in the membrane of both young and old rats have been studied. The obtained data allow us to suggest that 8 Hz EMF exposure has more pronounced age-dependent modulation effect on tissue hydration of heart muscle than 4 Hz EMF and this effect is sensitive to Na+/K+ pump activity and intracellular signaling system.

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4hz和8hz电磁场暴露对大鼠心肌组织水化作用的年龄依赖性比较研究

之前我们已经表明，4 Hz和8 Hz的EMF暴露对水的热力学活性具有抑制作用，从而减少过氧化物的形成。研究还表明，4Hz EMF处理的生理溶液调节微生物的生长发育和心肌收缩力，但8Hz EMF对细菌的生长发育具有显著的抑制作用。因此，为了阐明4Hz和8Hz EMF对心肌功能影响的可能机制，在本工作中，4Hz和5Hz EMF暴露对心肌组织水合作用的影响，研究了4 Hz和8 Hz EMF诱导的组织水合作用对10−4 M哇巴因（Na+/K+泵抑制）和10−9 M哇巴恩（细胞内信号系统激活）的敏感性，以及4 Hz和8Hz EMF暴露对年轻和老年大鼠膜中Na+/K＋泵单元数目的影响。所获得的数据使我们能够表明，与4Hz EMF相比，8Hz EMF暴露对心肌组织水合作用具有更明显的年龄依赖性调节作用，并且这种作用对Na+/K+泵活性和细胞内信号系统敏感。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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生物物理学期刊(英文)

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