Tinospora cordifolia: A New Perspective on Alzheimer’s disease and Green nanotechnology

IF 0.7 Q4 CHEMISTRY, MEDICINAL Natural Products Journal Pub Date : 2022-05-23 DOI:10.2174/2210315512666220523123836
Krishna Bhalodi, C. Kothari
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Abstract

Alzheimer’s disease (AD) is a common cause of dementia; the hallmark includes neuronal death and synaptic loss leading to cognitive decline. Up to date, there have been a vast number of preclinical & clinical trials based on natural compounds that play a crucial role in the prevention of AD. Tinospora cordifolia (Tc) is a medicinal plant with numerous bioactive properties used in Indian medicine. The literature study will scrutinized based on the disease-modifying effects of Tinospora cordifolia. It benefits the neurobiological researcher in understanding and researching the naturally occurring compound in combating AD. Furthermore, recent nanotechnology trends, such as green synthesis nanoparticles, have more potential in biomedical fields. Following that, the review draws attention to the Green synthesized nanoparticle of Tc, which has a wide range of applications.
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堇青花:阿尔茨海默病和绿色纳米技术的新视角
阿尔茨海默病(AD)是痴呆症的常见病因;其特征包括神经元死亡和突触丧失,导致认知能力下降。迄今为止,已经有大量基于天然化合物的临床前和临床试验,这些天然化合物在AD的预防中起着至关重要的作用。Tinospora cordifolia (Tc)是一种药用植物,具有许多生物活性,在印度医学中使用。本研究将以堇青花的抗病作用为基础进行文献研究。它有利于神经生物学研究者理解和研究抗阿尔茨海默病的天然化合物。此外,最近的纳米技术趋势,如绿色合成纳米粒子,在生物医学领域具有更大的潜力。接下来,综述了具有广泛应用前景的绿色合成纳米Tc颗粒。
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来源期刊
Natural Products Journal
Natural Products Journal CHEMISTRY, MEDICINAL-
CiteScore
1.70
自引率
0.00%
发文量
91
期刊介绍: The Natural Products Journal a peer reviewed journal, aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, full-length/mini reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.
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