{"title":"Issue Information","authors":"","doi":"10.1002/cpmc.85","DOIUrl":null,"url":null,"abstract":"<p><b>Cover</b>: In Grabowski and Kissinger et al. (http://doi.org/10.1002/cpmc.118), the image shows tick proteins from salivary glands and midguts provide ideal targets for countermeasure development. By using LC-MS/MS proteomics, proteins can be profiled from salivary glands, many of which can be secreted during blood feeding and found within the feeding site and the formed cement cone. Midgut proteins, especially exposed proteins in the lumen, provide critical areas for pathogen interactions and may aid in pathogen dissemination through the midgut epithelial layer to systemically infect the tick.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":39967,"journal":{"name":"Current Protocols in Microbiology","volume":"59 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/cpmc.85","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Protocols in Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cpmc.85","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cover: In Grabowski and Kissinger et al. (http://doi.org/10.1002/cpmc.118), the image shows tick proteins from salivary glands and midguts provide ideal targets for countermeasure development. By using LC-MS/MS proteomics, proteins can be profiled from salivary glands, many of which can be secreted during blood feeding and found within the feeding site and the formed cement cone. Midgut proteins, especially exposed proteins in the lumen, provide critical areas for pathogen interactions and may aid in pathogen dissemination through the midgut epithelial layer to systemically infect the tick.
期刊介绍：
Current Protocols in Microbiology provides detailed, step-by-step instructions for analyzing bacteria, animal and plant viruses, fungi, protozoans and other microbes. It offers updated coverage of emerging technologies and concepts, such as biofilms, quorum sensing and quantitative PCR, as well as proteomic and genomic methods. It is the first comprehensive source of high-quality microbiology protocols that reflects and incorporates the new mandates and capabilities of this robust and rapidly evolving discipline.
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